1,3-dimethyl-5,5-diphenyl-barbituric acid | 97846-22-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,3-dimethyl-5,5-diphenyl-barbituric acid
• 英文别名: 1,3-Dimethyl-5,5-diphenyl-barbitursaeure；1,3-bis(methyl)-5,5-diphenylbarbiturate；1,3-dimethyl-5,5-diphenyl-1,3-diazinane-2,4,6-trione
• CAS: 97846-22-5
• 化学式: C₁₈H₁₆N₂O₃
• 分子量: 308.337
• InChiKey: FIRNIXWQYFVBKZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  23
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  57.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  苯 在 重氮甲烷 、 乙醚 、 硫酸 、 三氧化硫 作用下， 生成 1,3-dimethyl-5,5-diphenyl-barbituric acid
  参考文献：
  名称：

  5,5-二苯基-巴比妥尔，5-苯基-5-环-己基-巴比妥尔和5-苯基-5-环-己烯基-巴比妥尔

  摘要：

  DOI：

  10.1002/hlca.193501801175

文献信息

• Novel oxopyrimidine derivatives, pharmaceutical compositions containing
  申请人：Taro Pharmaceutical Industries Ltd.

  公开号：US04628056A1

  公开（公告）日：1986-12-09

  There are disclosed novel oxopyrimidine derivatives of the general formula ##STR1## wherein R.sub.1 and R.sub.2 may be the same or different and are each hydrogen or lower alkyl optionally substituted by lower alkoxy, and R.sub.3 and R.sub.4 may be the same or different and are each phenyl optionally substituted by lower alkyl or halogen, provided that when R.sub.1 and R.sub.2 are both hydrogen, R.sub.3 and R.sub.4 are each substituted phenyl. Pharmaceutical compositions containing these compounds and their use as anticonvulsant, antianxiety and muscle relaxant agents are described.

  本发明涉及一种新型的氧代嘧啶衍生物，其一般式为##STR1##其中R.sub.1和R.sub.2可以相同或不同，分别为氢或低级烷基，可选地被低级烷氧基取代，而R.sub.3和R.sub.4可以相同或不同，分别为苯基，可选地被低级烷基或卤素取代，但当R.sub.1和R.sub.2都为氢时，R.sub.3和R.sub.4为取代的苯基。本发明还描述了含有这些化合物的药物组合物以及它们作为抗癫痫、抗焦虑和肌肉松弛剂的用途。
• Novel oxopyrimidine derivatives and pharmaceutical compositions containing them
  申请人：Taro Pharmaceutical Industries Ltd.

  公开号：EP0137343A2

  公开（公告）日：1985-04-17

  There are disclosed novel oxopyrimidine derivatives of the general formula wherein R, and R2 may be the same or different and are each hydrogen or lowel alkyl optionally substituted by lower alkoxy, and R3 and R4 may be the same or different and are each phenyl optionally substituted by lower alkyl or halogen, with the proviso that when R, and R2 are both hydrogen, R3 and R4 are each substituted phenyl. Pharmaceutical compositions containing these compounds are described. The compounds of the invention are active anticonvulsant, antianxiety and muscle relaxant agents.

  公开了通式如下的新型氧代嘧啶衍生物 其中，R和R2可以相同或不同，并且各自是氢或被低级烷氧基任选取代的低级烷基，R3和R4可以相同或不同，并且各自是被低级烷基或卤素任选取代的苯基，但当R和R2都是氢时，R3和R4各自是被取代的苯基。本文描述了含有这些化合物的药物组合物。本发明的化合物是活性抗惊厥剂、抗焦虑剂和肌肉松弛剂。
• Electrolyte and electrochemical device
  申请人：NINGDE AMPEREX TECHNOLOGY LIMITED

  公开号：US11031630B2

  公开（公告）日：2021-06-08

  The present application provides an electrolyte and an electrochemical device. The electrolyte according to the present application comprises a carboxylate, a barbituric acid compound and a nitrile compound. Adding a barbituric acid compound and a nitrile compound of particular structure to an electrolyte containing a carboxylate solvent can significantly improve the rate performance of an electrochemical device, and mitigate capacity loss after storage at room temperature, and cycle fading and gas generation at high-temperature of the electrochemical device.

  本申请提供了一种电解质和一种电化学装置。根据本申请，电解液由羧酸盐、巴比妥酸化合物和腈化合物组成。在含有羧酸盐溶剂的电解液中添加具有特定结构的巴比妥酸化合物和腈化合物，可显著提高电化学装置的速率性能，并可减轻电化学装置在室温储存后的容量损失以及高温下的循环衰减和气体生成。
• EP0137343B1
  申请人：——

  公开号：EP0137343B1

  公开（公告）日：1991-12-04
• ELECTROLYTE AND ELECTROCHEMICAL DEVICE
  申请人：NINGDE AMPEREX TECHNOLOGY LIMITED

  公开号：US20200243906A1

  公开（公告）日：2020-07-30

  The present application provides an electrolyte and an electrochemical device. The electrolyte according to the present application comprises a carboxylate, a barbituric acid compound and a nitrile compound. Adding a barbituric acid compound and a nitrile compound of particular structure to an electrolyte containing a carboxylate solvent can significantly improve the rate performance of an electrochemical device, and mitigate capacity loss after storage at room temperature, and cycle fading and gas generation at high-temperature of the electrochemical device.