2-甲基丁-3-烯-2-基(E)-3-(3,4-二羟基苯基)丙-2-烯酸酯 | 121496-68-2

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 中文名称: 2-甲基丁-3-烯-2-基(E)-3-(3,4-二羟基苯基)丙-2-烯酸酯
• 英文名称: Ddcae
• 英文别名: 2-methylbut-3-en-2-yl (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
• CAS: 121496-68-2
• 化学式: C₁₄H₁₆O₄
• 分子量: 248.27
• InChiKey: YNXBINXRYLBWOT-SOFGYWHQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  18
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  66.8
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• PROPOLIS AND EXTRACTS THEREOF FOR THE TREATMENT OF SKIN CANCERS AND IMPROVEMENT OF SKIN HEALTH
  申请人：Manuka Health New Zealand Limited

  公开号：EP3169321A1

  公开（公告）日：2017-05-24
• Propolis and Extracts Thereof for the Treatment of Skin Cancers and Improvement of Skin Health
  申请人：Manuka Health New Zealand Limited

  公开号：US20170209499A1

  公开（公告）日：2017-07-27

  This invention provides pharmaceutical and cosmeceutical compositions, including anti-skin cancer compositions, N containing propolis and cyclodextrin, and compositions comprising one or more compounds present in propolis, including compositions comprising one or more compounds present as an inclusion complex with cyclodextrin. Methods of using such compounds and compositions, in particular in the treatment or prevention of skin cancers and skin disorders, and in enhancing skin health, are also provided.
• [EN] PROPOLIS AND EXTRACTS THEREOF FOR THE TREATMENT OF SKIN CANCERS AND IMPROVEMENT OF SKIN HEALTH<br/>[FR] PROPOLIS ET EXTRAITS DE PROPOLIS POUR TRAITER LES CANCERS DE LA PEAU ET AMÉLIORER LA SANTÉ DE LA PEAU
  申请人：MANUKA HEALTH NEW ZEALAND LTD

  公开号：WO2016010440A1

  公开（公告）日：2016-01-21

  This invention provides pharmaceutical and cosmeceutical compositions, including anti-skin cancer compositions, containing propolis and cyclodextrin, and compositions comprising one or more compounds present in propolis, including compositions comprising one or more compounds present as an inclusion complex with cyclodextrin. Methods of using such compounds and compositions, in particular in the treatment or prevention of skin cancers and skin disorders, and in enhancing skin health, are also provided.