<(S)-2-amino-1-methoxyethyl> 6-amino-6-deoxy-α-D-glucopyranoside | 102088-82-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: <(S)-2-amino-1-methoxyethyl> 6-amino-6-deoxy-α-D-glucopyranoside
• CAS: 102088-82-4
• 化学式: C₉H₂₀N₂O₆
• 分子量: 252.268
• InChiKey: OJMFNKUJPQAJEM-LTUMISQWSA-N

反应信息

• 作为产物：
  描述：

  <(S)-2-azido-1-methoxyethyl> 6-azido-6-deoxy-α-D-glucopyranoside 在 platinum(IV) oxide 氢气 作用下， 反应 3.0h， 以98%的产率得到<(S)-2-amino-1-methoxyethyl> 6-amino-6-deoxy-α-D-glucopyranoside
  参考文献：
  名称：

  Comparative stability of 1-alkoxyalkyl α-d-glucosides in the presence of acid or α-d-glucosidase from yeast

  摘要：

  The aminated 1-alkoxyalkyl glycosides [(S)-2-amino-1-methoxyethyl] 6-amino-6-deoxy-alpha-D-glucopyranoside (3) and [(R,S)-1-ethoxyethyl] 6-amino-6-deoxy-alpha-D-glucopyranoside (4) have been synthesised and characterised. These compounds as well as [(R)-2-amino-1-methoxyethyl] alpha-D-glucopyranoside (1) prepared earlier are resistant against alpha-D-glucosidase (maltase, alpha-D-glucoside glucohydrolase, E.C. 3.2.1.20) from yeast, yet undergo hydrolysis under relatively mild acidic conditions. The kinetic parameters of the interaction with alpha-D-glucosidase and with acid were determined. The relative rates of acid hydrolysis of aminated 1-alkoxyalkyl glycosides compared with aminated ordinary glycosides suggest essential differences in the mechanism of acid-catalysed hydrolysis.

  DOI：

  10.1016/s0008-6215(00)90732-8