Imino<5-amino-1,3,4-oxadiazol-2-yl>carboxylic acid ethyl ester hydrochloride | 134318-59-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: Imino<5-amino-1,3,4-oxadiazol-2-yl>carboxylic acid ethyl ester hydrochloride
• 英文别名: ethyl 5-amino-1,3,4-oxadiazole-2-carboximidate;hydrochloride
• CAS: 134318-59-5
• 化学式: C₅H₈N₄O₂*ClH
• 分子量: 192.605
• InChiKey: SEVVHMXULRSERR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.44
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  98
• 氢给体数：
  3
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  Imino<5-amino-1,3,4-oxadiazol-2-yl>carboxylic acid ethyl ester hydrochloride 生成 5-amino-1,3,4-oxadiazole-2-carboxylic acid amide
  参考文献：
  名称：

  Synthesis of 2-amino-5-cyano-1,3,4-oxadiazole and some of its derivatives

  摘要：

  Preparative syntheses have been developed for 2-amino-5-cyano-1,3,4-oxadiazole from the semicarbazone of methyl glyoxylate and some of its transformations were studied. This product is an important intermediate in the preparation of its derivatives.

  DOI：

  10.1007/bf00959674
• 作为产物：
  描述：

  乙醇 、 5-氨基-1,3,4-恶二唑-2-甲腈 在 盐酸 作用下， 以 乙醚 为溶剂， 以97%的产率得到Imino<5-amino-1,3,4-oxadiazol-2-yl>carboxylic acid ethyl ester hydrochloride
  参考文献：
  名称：

  Synthesis of 2-amino-5-cyano-1,3,4-oxadiazole and some of its derivatives

  摘要：

  Preparative syntheses have been developed for 2-amino-5-cyano-1,3,4-oxadiazole from the semicarbazone of methyl glyoxylate and some of its transformations were studied. This product is an important intermediate in the preparation of its derivatives.

  DOI：

  10.1007/bf00959674

文献信息

• STOYANOVICH, F. M.;ZAXAROV, E. N.;LYSENKO, O. V.;YAROVENKO, V. N.;KRAYUSH+, IZV. AN CCCP. CEP. XIM.,(1991) N, S. 243-246
  作者：STOYANOVICH, F. M.、ZAXAROV, E. N.、LYSENKO, O. V.、YAROVENKO, V. N.、KRAYUSH+

  DOI：——

  日期：——