methyl 2-acetamido-2-deoxy-3-O-methyl-β-D-glucopyranoside | 10427-80-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: methyl 2-acetamido-2-deoxy-3-O-methyl-β-D-glucopyranoside
• 英文别名: Methyl-2-acetamido-3-O-methyl-2-deoxy-β-D-glucopyranosid；Methyl-N-acetyl-3-O-methyl-β-D-glucosaminid；methyl-(2-acetylamino-O³-methyl-2-deoxy-β-D-glucopyranoside)；Methyl-(2-acetylamino-O³-methyl-2-desoxy-β-D-glucopyranosid)
• CAS: 10427-80-2
• 化学式: C₁₀H₁₉NO₆
• 分子量: 249.264
• InChiKey: NQZUQHYRSVKBRT-VVULQXIFSA-N

反应信息

• 作为反应物：
  描述：

  methyl 2-acetamido-2-deoxy-3-O-methyl-β-D-glucopyranoside 在 盐酸 作用下， 生成 2-amino-O³-methyl-2-deoxy-α-D-glucopyranose; hydrochloride
  参考文献：
  名称：

  12.高碘酸对氨基葡萄糖衍生物的作用

  摘要：

  DOI：

  10.1039/jr9410000047
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 溶剂黄146 作用下， 生成 methyl 2-acetamido-2-deoxy-3-O-methyl-β-D-glucopyranoside
  参考文献：
  名称：

  Studies on Amino-hexoses. IX. TheN-Deacetylation of MethylN-Acetyl-β-D-glucosaminide, MethylN-Acetyl-3-O-methyl-α- and β-D-glucosaminide, and MethylN-Acetyl-4,6-O-ethylidene-α-D-glcosaminide

  摘要：

  在肼与四种N-乙酰氨基糖的反应中，肼作为温和的N-脱乙酰化试剂的效率得到了研究。该试剂已被证明在甲基N-乙酰-β-d-氨基葡萄糖苷和甲基N-乙酰-4,6-O-亚乙基-α-d-氨基葡萄糖苷的N-脱乙酰化中具有很大的用途。值得注意的是，糖的3-O-取代使得脱乙酰化反应变得不情愿。甲基N-乙酰-4,6-O-亚乙基-α-d-氨基葡萄糖苷的合成和结晶甲基β-d-氨基葡萄糖苷和甲基4,6-O-亚乙基-α-d-氨基葡萄糖苷的游离碱形式的分离已经得到描述。

  DOI：

  10.1246/bcsj.39.185

文献信息

• Glycosides of 2-Acetamido-2-deoxy-D-glucosamine and Benzylidene Derivatives
  作者：Wolfgang Roth、Ward Pigman

  DOI：10.1021/ja01502a041

  日期：1960.9

  The methylation of 2-acetamido-2-deoxy-4,6-O-benzylidene-D-glucopyranose is a convenient method for the preparation of pure methyl alpha- and beta-glycosides of D-glucosamine. The anomeric configuration of the glycosides depends on the solvent. New physical constants are given for 2-acetamido-2-deoxy-4,6-O-benzylidene-D-glueopyranose, methyl. 2-acetamido-2-deoxy-4,6-O-benzylidene-beta-D-glucopyranoside, methyl 2-acetamido-2-deoxy-3-O-methyl-4,6-O-benzylidene-beta-D-glucopyranoside, methyl 2-acetamido-2-deoxy-4,6-0-benzylidene-a-D-glucopyranoside. The following new compounds are described: methyl 2-acetamido-2-deoxy-5,6-O-benzylidene-beta-D-glucofuranoside, methyl 2-acetamido-2-deoxy-3-O-methyl-5,6-O-benzylidene-beta-D-glucofuranoside and methyl 2-acetamido-2-deoxy-3-O-methyl-beta-D-glucofuranoside.
• Masamune et al., Tohoku Journal of Experimental Medicine, 1958, vol. 68, p. 181
  作者：Masamune et al.

  DOI：——

  日期：——