| 1360156-03-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 1360156-03-1
• 化学式: C₅₆H₈₁N₅O₃₆
• 分子量: 1400.27
• InChiKey: LMLURKTZMUXAJU-PNYIQPLZSA-N

反应信息

• 作为产物：
  描述：

  在 甲醇 、 sodium methylate 作用下， 以80%的产率得到
  参考文献：
  名称：

  β-Cyclodextrin as a mimetic of the natural GFP-chromophore environment

  摘要：

  The green fluorescent protein (GFP) chromophore has been anchored to beta-cyclodextrin (beta CD) via a copper(I)-catalyzed azide-alkyne cycloaddition. The photophysical properties of this new GFP-CD derivative have been evaluated, showing the formation of a self-inclusion complex and enhancement of fluorescence of the GFP-chromophore covalently bound to the beta CD. This enhancement of fluorescence by encapsulation and hence fixation of the chromophore in a binding pocket mimics the effect exerted by the natural protein environment. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.12.053