(-)-N-(2,3;5,6-di-O-isopropylidene-β-D-mannofuranosyl)hydroxylamine | 372511-67-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (-)-N-(2,3;5,6-di-O-isopropylidene-β-D-mannofuranosyl)hydroxylamine
• CAS: 372511-67-6
• 化学式: C₁₂H₂₁NO₆
• 分子量: 275.302
• InChiKey: FLWZKKRGBHCGBS-FHNUBNKASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.36
• 重原子数：
  19.0
• 可旋转键数：
  2.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  78.41
• 氢给体数：
  2.0
• 氢受体数：
  7.0

反应信息

• 作为反应物：
  描述：

  (-)-N-(2,3;5,6-di-O-isopropylidene-β-D-mannofuranosyl)hydroxylamine 、 Phenylphosphinsaeure-monophenylester 在 吡啶 作用下， 以 氯仿 为溶剂， 反应 6.0h， 以35%的产率得到1-deoxy-1-phenyl(phenoxy)phosphoryl-1-hydroxylamino-2,3;5,6-di-O-isopropylidene-D-mannitol
  参考文献：
  名称：

  Hydrophosphorylation of monosaccharides oximes and hydrazones

  摘要：

  The hydrophosphorylation of monosaccharides oximes and hydrazones was studied; similarity and difference of this process compared to the reaction of secondary glycosylamines with the hydrophosphoryl compounds are shown. A number of the original alpha-aminophosphoryl compounds is obtained including those containing carbohydrate fragment in their compositions.

  DOI：

  10.1134/s1070363209080064
• 作为产物：
  描述：

  2,3:5,6-二-O-异亚丙基-D-甘露呋喃糖 在 盐酸羟胺 作用下， 以69%的产率得到(-)-N-(2,3;5,6-di-O-isopropylidene-β-D-mannofuranosyl)hydroxylamine
  参考文献：
  名称：

  Hydrophosphorylation of monosaccharides oximes and hydrazones

  摘要：

  The hydrophosphorylation of monosaccharides oximes and hydrazones was studied; similarity and difference of this process compared to the reaction of secondary glycosylamines with the hydrophosphoryl compounds are shown. A number of the original alpha-aminophosphoryl compounds is obtained including those containing carbohydrate fragment in their compositions.

  DOI：

  10.1134/s1070363209080064