左氧氟沙星二胺 | 1797510-34-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 中文名称: 左氧氟沙星二胺
• 英文名称: (S)-10-((2-aminoethyl)amino)-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxaazino[2,3,4-ij]quinoline-6-carboxylic acid
• 英文别名: (2S)-6-(2-aminoethylamino)-7-fluoro-2-methyl-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid
• CAS: 1797510-34-9
• 化学式: C₁₅H₁₆FN₃O₄
• 分子量: 321.308
• InChiKey: TUQVWTUNZIJAQI-ZETCQYMHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.3
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  105
• 氢给体数：
  3
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  盐酸左氧氟沙星 在 氧气 作用下， 以 水 为溶剂， 反应 1.0h， 生成 、 、 、 、 左氧氟沙星二胺 、 、 、 、 、 左氧氟沙星USP杂质B 、 N,N’-去乙烯-N,N’-二甲酰基左氧氟沙星
  参考文献：
  名称：

  Visible light-driven photocatalytic degradation of organic pollutants by a novel Ag3VO4/Ag2CO3 p–n heterojunction photocatalyst: Mechanistic insight and degradation pathways

  摘要：

  In the field of photocatalysis, the construction of a heterojunction system with efficient charge separation at the interface and charge transfer to increase the photocatalyst performance has gained considerable attention. In this study, the Ag3VO4/Ag(2)CO(3 )p-n heterojunction is first synthesized using a simple coprecipitation method. The composite photocatalyst with a p-n heterojunction has a strong internal electric field, and its strong driving force can effectively solve the problem of low separation and migration efficiency of photogenerated electron-hole pairs. The optimized Ag3VO4/Ag2CO3 composite can effectively degrade organic pollutants (rhodamine b (RhB), methylene blue (MB), levofloxacin (LVF), and tetracycline). More specifically, the Ag3VO4/Ag2CO3 photocatalyst with a 1:2 mass ratio (VC-12) can remove 97.8% and 82% of RhB and LVF within 30 and 60 min, respectively. The LVF degradation rate by VC-12 under visible light irradiation is more than 12.8 and 21.51 times higher than those of pure Ag3VO4 and Ag2CO3, respectively. The excellent photocatalytic activity of the Ag3VO4/Ag2CO3 hybrid system is mainly attributed to the internal electric field that forms in the Ag3VO4/Ag2CO3 p-n heterojunction system, the photogenerated electron hole pairs that separate and facilely migrate, and the specific surface area of VC-12 that is larger than that of the monomer. In addition, the degradation efficiency of VC-12 did not decline significantly after four cycles. In this study, the photocatalytic mechanism for Ag3VO4/Ag2CO3 photocatalysts is explored in detail based on the energy band analysis results, trapping experiment results, and electron spin resonance spectra. Finally, the LVF degradation products are analyzed by liquid chromatography-mass spectrometry, and the potential LVF degradation pathway is identified. The experiments performed in this research therefore lead to new motivation for the design and synthesis of highly efficient and widely applicable photocatalysts for environmental purification. (C) 2020 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jallcom.2020.155211