1-(ethylsulfanyl)pentan-2-ol | 1159011-14-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-(ethylsulfanyl)pentan-2-ol
• 英文别名: 1-ethylsulfanylpentan-2-ol
• CAS: 1159011-14-9
• 化学式: C₇H₁₆OS
• 分子量: 148.269
• InChiKey: AHICEDSVMUCDLG-UHFFFAOYSA-N

物化性质

• 沸点：
  82-84 °C(Press: 2 mmHg)
• 密度：
  0.950±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  9
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  45.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  环己亚胺 、 聚合甲醛 、 1-(ethylsulfanyl)pentan-2-ol 以 苯 为溶剂， 以72%的产率得到2-(hexamethyleneiminomethoxy)-1(ethylsulfanyl)pentane
  参考文献：
  名称：

  Synthesis and properties of aminomethoxyderivatives of 1-ethylthiopentane

  摘要：

  Previously unknown aminomethoxy derivatives of 1-ethylthiopentane were synthesized by the three-component Mannich reaction of 1-ethylthiopentanol with formaldehyde in the presence of secondary amines and they were characterized. The structure of the compounds obtained was established by means of elemental analysis, IR and H-1 NMR spectroscopy, and mass spectrometry. The products synthesized were tested as antimicrobial additives to lubricants and antiseptic substances against bacteria and fungi. They are more effective antimicrobial agents than the preparations which are nowadays used in practice.

  DOI：

  10.1134/s1070363212110084
• 作为产物：
  描述：

  1-溴戊烷-2-醇 、 乙硫醇 在 sodium hydroxide 作用下， 以 水 为溶剂， 反应 3.0h， 以62%的产率得到1-(ethylsulfanyl)pentan-2-ol
  参考文献：
  名称：

  Synthesis and properties of aminomethoxyderivatives of 1-ethylthiopentane

  摘要：

  Previously unknown aminomethoxy derivatives of 1-ethylthiopentane were synthesized by the three-component Mannich reaction of 1-ethylthiopentanol with formaldehyde in the presence of secondary amines and they were characterized. The structure of the compounds obtained was established by means of elemental analysis, IR and H-1 NMR spectroscopy, and mass spectrometry. The products synthesized were tested as antimicrobial additives to lubricants and antiseptic substances against bacteria and fungi. They are more effective antimicrobial agents than the preparations which are nowadays used in practice.

  DOI：

  10.1134/s1070363212110084

文献信息

• Synthesis and properties of aminomethoxyderivatives of 1-ethylthiopentane
  作者：E. G. Mamedbeili、I. A. Dzhafarov、T. G. Kyazimova、S. I. Ibragimli、Kh. I. Gasanov

  DOI：10.1134/s1070363212110084

  日期：2012.11

  Previously unknown aminomethoxy derivatives of 1-ethylthiopentane were synthesized by the three-component Mannich reaction of 1-ethylthiopentanol with formaldehyde in the presence of secondary amines and they were characterized. The structure of the compounds obtained was established by means of elemental analysis, IR and H-1 NMR spectroscopy, and mass spectrometry. The products synthesized were tested as antimicrobial additives to lubricants and antiseptic substances against bacteria and fungi. They are more effective antimicrobial agents than the preparations which are nowadays used in practice.