1,2-di-O-benzyl-3-O-[4'-O-(2'',3'',4'',6''-tetra-O-acetyl-α-D-glucopyranosyl)-2',3',6'-tri-O-acetyl-β-D-glucopyranosyl]-sn-glycerol | 429677-89-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油脂
• 英文名称: 1,2-di-O-benzyl-3-O-[4'-O-(2'',3'',4'',6''-tetra-O-acetyl-α-D-glucopyranosyl)-2',3',6'-tri-O-acetyl-β-D-glucopyranosyl]-sn-glycerol
• CAS: 429677-89-4
• 化学式: C₄₃H₅₄O₂₀
• 分子量: 890.89
• InChiKey: XZFRWHZFYDZLPL-JRVPVTHQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.42
• 重原子数：
  63.0
• 可旋转键数：
  21.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  239.48
• 氢给体数：
  0.0
• 氢受体数：
  20.0

反应信息

• 作为反应物：
  描述：

  1,2-di-O-benzyl-3-O-[4'-O-(2'',3'',4'',6''-tetra-O-acetyl-α-D-glucopyranosyl)-2',3',6'-tri-O-acetyl-β-D-glucopyranosyl]-sn-glycerol 在 palladium on activated charcoal 甲醇 、 氢气 、 sodium methylate 、 对甲苯磺酸 作用下， 以 乙醇 、 溶剂黄146 、 乙酸乙酯 、 丙酮 为溶剂， 20.0 ℃ 、101.33 kPa 条件下， 生成 (2R,3R,4S,5S,6R)-2-[(2R,3S,4R,5R,6R)-6-((S)-2,2-Dimethyl-[1,3]dioxolan-4-ylmethoxy)-4,5-dihydroxy-2-hydroxymethyl-tetrahydro-pyran-3-yloxy]-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol
  参考文献：
  名称：

  Synthesis and mesogenic properties of glycosyl diacylglycerols

  摘要：

  We synthesised glycosyl diacylglycerols bearing unsaturated or chiral methyl branched fatty acid chains. The thermotropism was measured with polarising microscopy and additionally the lyotropism with the contact preparation method. The synthesised compounds displayed thermotropic S-A (lamellar), cubic and columnar phases and investigation of the lyotropic phase behaviour led to the observation of inverted bicontinuous cubic V-H phases, lamellar L-x phases and normal bicontinuous cubic V-I phases, The phases are discussed with respect to the chemical structures that have been varied systematically to derive structure-property relationships. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.

  DOI：

  10.1016/s0009-3084(01)00202-x
• 作为产物：
  描述：

  (S)-(-)-2,3-二苄氧基-1-丙醇 、 2,3,6,2',3',4',6'-hepta-O-acetyl-α-D-maltosyl bromide 在 氰化汞 、 mercury dibromide 作用下， 以 乙腈 为溶剂， 以65%的产率得到1,2-di-O-benzyl-3-O-[4'-O-(2'',3'',4'',6''-tetra-O-acetyl-α-D-glucopyranosyl)-2',3',6'-tri-O-acetyl-β-D-glucopyranosyl]-sn-glycerol
  参考文献：
  名称：

  Synthesis and mesogenic properties of glycosyl diacylglycerols

  摘要：

  We synthesised glycosyl diacylglycerols bearing unsaturated or chiral methyl branched fatty acid chains. The thermotropism was measured with polarising microscopy and additionally the lyotropism with the contact preparation method. The synthesised compounds displayed thermotropic S-A (lamellar), cubic and columnar phases and investigation of the lyotropic phase behaviour led to the observation of inverted bicontinuous cubic V-H phases, lamellar L-x phases and normal bicontinuous cubic V-I phases, The phases are discussed with respect to the chemical structures that have been varied systematically to derive structure-property relationships. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.

  DOI：

  10.1016/s0009-3084(01)00202-x