4-methoxyphenyl 2-acetamido-2-deoxy-β-D-galactopyranosyl-(1-4)-α-D-galactopyranosyl-(1-3)-2-acetamido-2-deoxy-β-D-galactopyranosyl-(1-6)-[α-L-fucopyranosyl-(1-2)]-β-D-galactopyranoside | 1256157-10-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 4-methoxyphenyl 2-acetamido-2-deoxy-β-D-galactopyranosyl-(1-4)-α-D-galactopyranosyl-(1-3)-2-acetamido-2-deoxy-β-D-galactopyranosyl-(1-6)-[α-L-fucopyranosyl-(1-2)]-β-D-galactopyranoside
• 英文别名: 4-methoxyphenyl 2-acetamido-2-deoxy-β-D-galactopyranosyl-(1->4)-α-D-galactopyranosyl-(1->3)-2-acetamido-2-deoxy-β-D-galactopyranosyl-(1->6)-[α-L-fucopyranosyl-(1->2)]-β-D-galactopyranoside
• CAS: 1256157-10-4
• 化学式: C₄₁H₆₄N₂O₂₆
• 分子量: 1000.96
• InChiKey: PWXAYBZRHOHMDW-AWRNNQAPSA-N

反应信息

• 作为产物：
  描述：

  4-methoxyphenyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-galactopyranosyl-(1-4)-2,3,6-tri-O-acetyl-α-D-galactopyranosyl-(1-3)-2-acetamido-4,6-di-O-acetyl-2-deoxy-β-D-galactopyranosyl-(1-6)-[2,3,4-tri-O-acetyl-α-L-fucopyranosyl-(1-2)]-3,4-di-O-acetyl-β-D-galactopyranoside 在 sodium methylate 作用下， 以 甲醇 为溶剂， 反应 10.0h， 以92%的产率得到4-methoxyphenyl 2-acetamido-2-deoxy-β-D-galactopyranosyl-(1-4)-α-D-galactopyranosyl-(1-3)-2-acetamido-2-deoxy-β-D-galactopyranosyl-(1-6)-[α-L-fucopyranosyl-(1-2)]-β-D-galactopyranoside
  参考文献：
  名称：

  Synthesis of the pentasaccharide repeating unit of Escherichia coli O128 antigen

  摘要：

  A pentasaccharide, 4-methoxyphenyl 2-acetamido-2-deoxy-beta-D-galactoPyranosyl-(1 -> 4)-alpha-D-galactopyranosyl-(1 -> 3)-2-acetamido-2-deoxy-beta-D-galactoPyranosyl-(1 -> 6)-[alpha-L-fucopyranosyl-(1 -> 2)]-beta-D-galactopyranoside (1), representing the repeating unit of Escherichia coli O128 antigen, was successfully prepared in 23% overall yield via a convergent '2+3' glycosylation strategy. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2010.07.025