1-Bromo-1,1-difluorotridec-2-yn-4-ol | 1042744-23-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-Bromo-1,1-difluorotridec-2-yn-4-ol
• CAS: 1042744-23-9
• 化学式: C₁₃H₂₁BrF₂O
• 分子量: 311.21
• InChiKey: QTFOTIIYLLBOIH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  17
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.85
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• COMPOSITIONS AND METHODS FOR MODULATING DNMT1 INHIBITOR ACTIVITY
  申请人：UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.

  公开号：US20150238439A1

  公开（公告）日：2015-08-27

  Some aspects of the invention include attenuating DNMT1 inhibitor activity in an animal comprising administering an antioxidant. Other aspects of the invention include methods comprising administering a composition comprising a DNMT1 inhibitor and an antioxidant. In some instances in the methods, the animal is undergoing a treatment for cancer. Additional aspects of the invention include compositions comprising a DNMT1 inhibitor and an antioxidant.
• [EN] COMPOSITIONS AND METHODS FOR MODULATING DNMT1 INHIBITOR ACTIVITY<br/>[FR] COMPOSITIONS ET MÉTHODES DE MODULATION DE L'ACTIVITÉ INHIBITRICE DE LA DNMT1
  申请人：UNIV LOUISVILLE RES FOUND

  公开号：WO2014039860A2

  公开（公告）日：2014-03-13

  Some aspects of the invention include attenuating DNMTl inhibitor activity in an animal comprising administering an antioxidant. Other aspects of the invention include methods comprising administering a composition comprising a DNMTl inhibitor and an antioxidant. In some instances in the methods, the animal is undergoing a treatment for cancer. Additional aspects of the invention include compositions comprising a DNMTl inhibitor and an antioxidant.