(2,4-dinitrophenyl)(pyridin-2-yl)methanone | 68902-03-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2,4-dinitrophenyl)(pyridin-2-yl)methanone
• 英文别名: 2-(2',4'-Dinitrobenzoyl)-pyridin；(2,4-Dinitrophenyl)-pyridin-2-ylmethanone；(2,4-dinitrophenyl)-pyridin-2-ylmethanone
• CAS: 68902-03-4
• 化学式: C₁₂H₇N₃O₅
• 分子量: 273.205
• InChiKey: QTWDYLLCDGDTJE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  20
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  122
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  2-(对硝基苄基)吡啶 在 硫酸 、 硝酸 、 permanganate(VII) ion 作用下， 生成 (2,4-dinitrophenyl)(pyridin-2-yl)methanone
  参考文献：
  名称：

  Tschitschibabin; Kuindshi; Benewolenskaja, Chemische Berichte, 1925, vol. 58, p. 1585

  摘要：

  DOI：

文献信息

• Efficient Selenium-Catalyzed Selective C(sp³)−H Oxidation of Benzylpyridines with Molecular Oxygen
  作者：Weiwei Jin、Poonnapa Zheng、Wing-Tak Wong、Ga-Lai Law

  DOI：10.1002/adsc.201601065

  日期：2017.5.2

  An efficient selenium‐catalyzed direct oxidation of benzylpyridines in aqueous DMSO has been successfully developed by using molecular oxygen as the oxidant. A variety of benzoylpyridines with broad functional group tolerance were obtained in modest to excellent yields and with exclusive chemoselectivity.

  通过使用分子氧作为氧化剂，成功开发了一种有效的硒催化的DMSO水溶液中苄基吡啶的直接氧化方法。获得了各种具有宽泛的官能团耐受性的苯甲酰基吡啶，其收率适中至优异，并且具有独特的化学选择性。
• Synergistic H₄NI–AcOH Catalyzed Oxidation of the C_sp³–H Bonds of Benzylpyridines with Molecular Oxygen
  作者：Lanhui Ren、Lianyue Wang、Ying Lv、Guosong Li、Shuang Gao

  DOI：10.1021/acs.orglett.5b00602

  日期：2015.5.1

  The oxidation of benzylpyridines forming benzoylpyridines was achieved based on a synergistic H4NI-AcOH catalyst and molecular oxygen in high yield under solvent-free conditions. This is the first nonmetallic catalytic system for this oxidation transformation using molecular oxygen as the oxidant. The catalytic system has a wide scope of substrates and excellent chemoselectivity, and this procedure can also be scaled up. The study of a preliminary reaction mechanism demonstrated that the oxidation of the C-sp(3)-H bonds of benzylpyridines was promoted by the pyridinium salts formed by AcOH and benzylpyridines. The synergistic effect of H4NI-AcOH was also demonstrated by control experiments.
• Tschitschibabin; Kuindshi; Benewolenskaja, Chemische Berichte, 1925, vol. 58, p. 1585
  作者：Tschitschibabin、Kuindshi、Benewolenskaja

  DOI：——

  日期：——