7-(3-hydroxy-4-methoxyphenyl)-10,11-dihydrobenzo[c]acridin-8(7H,9H,12H)-one | 1236350-90-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 7-(3-hydroxy-4-methoxyphenyl)-10,11-dihydrobenzo[c]acridin-8(7H,9H,12H)-one
• CAS: 1236350-90-5
• 化学式: C₂₄H₂₁NO₃
• 分子量: 371.436
• InChiKey: XRRHBOZTOAEIEB-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  、 1,3-环己二酮 以 正丁醇 为溶剂， 以50%的产率得到7-(3-hydroxy-4-methoxyphenyl)-10,11-dihydrobenzo[c]acridin-8(7H,9H,12H)-one
  参考文献：
  名称：

  Synthesis of 7-[4-alkoxy-3-methoxy(hydroxy)phenyl]-10,11-dihydrobenzo[c]acridin-8(7H,9H,12H)-ones and 4-(8-oxo-7,8,9,10,11,12-hexahydrobenzo[c]acridin-7-yl)-2-methoxy(ethoxy)phenyl esters of carboxylic acids

  摘要：

  Reactions of azomethines (Schiff bases) prepared from vanillin and vanillal ethers and 1-naphthylamine with cyclohexane-1,3-dione in butanol afforded in 40-64% yields 7-[4-alkoxy-3-methoxy(hydroxy)phenyl]-10,11-dihydrobenzo[c]acridin-8(7H,9H,12H)-ones and 4-(8-oxo-7,8,9,10,11,12-hexahydrobenzo[C]acridin-7-yl)-2-methoxy(ethoxy)phenyl esters of carboxylic acids. The reaction products presumably formed by the rearrangement of the azomethine adduct with the cyclohexane-1,3-dione proceeding by the type of Hofmann-Martius rearrangement. The structure of compounds synthesized was confirmed by the elemental analysis, UV, IR, and H-1 NMR spectra.

  DOI：

  10.1134/s1070428010050234