blocked p-nitrophenyl maltoheptaoside | 109055-07-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: blocked p-nitrophenyl maltoheptaoside
• 英文别名: (4aR,6R,7R,8R,8aS)-6-[(2R,3S,4R,5R,6R)-6-[(2R,3S,4R,5R,6R)-6-[(2R,3S,4R,5R,6R)-6-[(2R,3S,4R,5R,6R)-6-[(2R,3S,4R,5R,6R)-6-[(2R,3S,4R,5R,6R)-4,5-dihydroxy-2-(hydroxymethyl)-6-(4-nitrophenoxy)oxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-2-phenyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxine-7,8-diol
• CAS: 109055-07-4
• 化学式: C₅₅H₇₉NO₃₈
• 分子量: 1362.22
• InChiKey: XCJLWZRXMYZWON-OYMNYBAJSA-N

物化性质

• 密度：
  1.79±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -11.4
• 重原子数：
  94
• 可旋转键数：
  21
• 环数：
  10.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  598
• 氢给体数：
  20
• 氢受体数：
  38

反应信息

• 作为反应物：
  描述：

  blocked p-nitrophenyl maltoheptaoside 以 水 为溶剂， 生成 对硝基苯基麦芽糖苷 、 对硝基苯酚 、 对硝基苯-α-D-葡萄糖吡喃苷
  参考文献：
  名称：

  The action of germinated barley alpha-amylases on linear maltodextrins

  摘要：

  The actions of barley alpha-amylase isozymes 1 and 2 (EC 3.2.1.1) on malto-oligosaccharides and their p-nitrophenyl glycosides were similar, but not identical. For each isozyme, transglycosylation occurred with small substrates that were hydrolysed with difficulty, whereas the rates of hydrolysis increased with increase in the size of the substrate for both the malto-oligosaccharides and the p-nitrophenyl glycosides. A p-nitrophenyl group was found to mimic a glucose residue to a large extent. The differences in action of the isozymes are believed to be caused by differences at more than one subsite of the active site. A lysine-arginine substitution is postulated to account for some of the observed variations.

  DOI：

  10.1016/0008-6215(92)85080-j