11,23-diamino-25,27-dihydroxy-26,28-dimethoxycalix[4]arene | 148033-39-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 11,23-diamino-25,27-dihydroxy-26,28-dimethoxycalix[4]arene
• CAS: 148033-39-0
• 化学式: C₃₀H₃₀N₂O₄
• 分子量: 482.579
• InChiKey: BDAAJEQGGWVHSE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.96
• 重原子数：
  36.0
• 可旋转键数：
  2.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  110.96
• 氢给体数：
  4.0
• 氢受体数：
  6.0

反应信息

• 作为反应物：
  描述：

  11,23-diamino-25,27-dihydroxy-26,28-dimethoxycalix[4]arene 、 2,2'-bipyridine-5-carbonyl chloride 以75%的产率得到N,N'-(12,52-dihydroxy-32,72-dimethoxy-1,3,5,7(1,3)-tetrabenzenacyclooctaphane-15,55-diyl)bis([2,2'-bipyridine]-4-carboxamide)
  参考文献：
  名称：

  新型钌（II）联吡啶杯[4]芳烃受体分子对阴离子的识别

  摘要：

  已经制备了含有一个和两个钌（II）联吡啶基部分的异杯异色杯[4]芳烃单和双主题阴离子受体，并通过1 H NMR和CV证明其结合并电化学识别卤化物，磷酸二氢根和硫酸氢根阴离子。所述monotopic杯[4]芳烃阴离子受体8选择性电化学识别ħ 2 PO 4 -中的十倍过量HSO的存在4 -和Cl - 。

  DOI：

  10.1039/c39940001269
• 作为产物：
  描述：

  26,28-dimethoxycalix[4]arene-25,27-diol 在 镍 硝酸 、 一水合肼 、 溶剂黄146 作用下， 以 二氯甲烷 为溶剂， 生成 11,23-diamino-25,27-dihydroxy-26,28-dimethoxycalix[4]arene
  参考文献：
  名称：

  Dicarboxylate anion recognition by a redox-responsive ditopic bis(cobalticinium) calix[4]arene receptor molecule

  摘要：

  我们制备了一种新型钙[4]炔二元阴离子受体分子，其中含有两个钴吟分子，并通过 1H NMR 和循环伏安法证明，该分子能够配位和电化学识别阴离子，包括二羧酸根二元阴离子己二酸盐。

  DOI：

  10.1039/c39930000229

文献信息

• Anion Recognition by Redox-Responsive Ditopic Bis-Cobaltocenium Receptor Molecules Including a Novel Calix[4]arene Derivative That Binds a Dicarboxylate Dianion
  作者：Paul D. Beer、Dusan Hesek、Justine E. Kingston、David K. Smith、Sally E. Stokes、Michael G. B. Drew

  DOI：10.1021/om00007a032

  日期：1995.7

  A series of novel ditopic bis-cobaltocenium receptor molecules containing alkyl, aryl, and calix[4]arene spacers have been synthesized via the reaction of the new synthon 1-(ethylcarboxy)-1'-(chlorocarbonyl)cobaltocenium chloride (3) or 1-(chloro carbonyl)cobaltocenium chloride (9) with the appropriate diamine. Proton NMR halide anion coordination studies reveal that the ethyl- (4), propyl- (5), and butyl-linked (6) derivatives form 1:1 stoichiometric complexes in acetonitrile solutions. Stability constant determinations suggest that the ethyl derivative 4 exhibits selectivity for the chloride anion in preference to bromide or iodide. Receptors containing larger aryl (7,8,10) and alkylamino (11) spacers form complexes of2:1 halide anion:receptor stoichiometry. An X-ray crystal structure of the bis-cobaltocenium calix[4]arene derivative 15 is described. This receptor forms extremely stable 1:1 anion complexes with chloride, bromide, and H2PO4- in dimethylsulfoxide solutions and with the dicarboxylate dianion adipate in acetone. Ah the bis-cobaltocenium systems were found to display electrochemical recognition of varied anion guests, as shown by cyclic voltammetric experiments. Receptor 15 was also found to redox-respond to the presence of adipate.