3-(2-quinolyl)benzene-1,2-diol | 756900-91-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 3-(2-quinolyl)benzene-1,2-diol
• 英文别名: 3-[2]quinolyl-pyrocatechol；3-[2]Chinolyl-brenzcatechin；3-(Quinolin-2-YL)benzene-1,2-diol；3-quinolin-2-ylbenzene-1,2-diol
• CAS: 756900-91-1
• 化学式: C₁₅H₁₁NO₂
• 分子量: 237.258
• InChiKey: ICCXBEIMPOMWON-UHFFFAOYSA-N

物化性质

• 熔点：
  209-210 °C
• 沸点：
  450.8±40.0 °C(Predicted)
• 密度：
  1.326±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  18
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  53.4
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2-苯基喹啉 在 葡萄糖 、 异丙基-beta-D-硫代半乳糖吡喃糖苷 Escherichia coli JM₁₀₉ harboring plasmid pBS₂₀₇₂B 、 M₉ medium 、 维生素B1 作用下， 以31%的产率得到3-(2-quinolyl)benzene-1,2-diol
  参考文献：
  名称：

  Synthesis of vicinal diols from various arenes with a heterocyclic, amino or carboxyl group by using recombinant Escherichia coli cells expressing evolved biphenyl dioxygenase and dihydrodiol dehydrogenase genes

  摘要：

  Various aromatic molecules, in which heterocycles are linked with a phenyl or benzyl group, were converted to their respective 2,3-diols (catechols) in the benzene ring by growing cell reactions using recombinant Escherichia coli, which expressed the evolved biphenyl dioxygenase [bphA (2072)] genes and the subsequent bacterial dihydrodiol dehydrogenase (bphB) gene. These vicinal diol products showed strong in vitro inhibitory activity against the lipid peroxidation induced by free radicals and strong scavenging activity towards DPPH radicals. The vicinal diols were also synthesized from ionized monocyclic aromatics incorporating an amino or carboxyl group. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2004.10.052

文献信息

• Blends of a thermotropic copolyester and a thermotropic copoly(ester–amide): structure and mechanical properties
  作者：F.J. Vallejo、J.I. Eguiazábal、J. Nazábal

  DOI：10.1016/s0032-3861(01)00475-x

  日期：2001.11

  Rodrun 5000/Vectra B950 blends were obtained by direct injection moulding at two injections rates. The blends were partially miscible and unreacted under the processing conditions used. Higher orientations and properties were obtained at the lower injection rate due to the higher overall orientation obtained. The produced orientation and the negative volume of mixing of the blends led to a range of

  Rodrun 5000 / Vectra B950共混物是通过两次注射速率的直接注塑成型获得的。该共混物在使用的加工条件下是部分可混溶的并且未反应。由于获得了较高的总体取向，因此在较低的注射速率下可以获得较高的取向和性能。所产生的取向和共混物的负混合量导致了一系列LCP材料，它们具有中等的模量和拉伸强度以及略高的延展性。

表征谱图