S-(1-adamantyl) 4-propan-2-ylbenzenecarbothioate | 1264748-34-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: S-(1-adamantyl) 4-propan-2-ylbenzenecarbothioate
• CAS: 1264748-34-6
• 化学式: C₂₀H₂₆OS
• 分子量: 314.492
• InChiKey: DXDWDJXUWVQHBK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.1
• 重原子数：
  22
• 可旋转键数：
  4
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.65
• 拓扑面积：
  42.4
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  1-金刚烷醇 、 (4-isopropylphenyl)(morpholino)methanethione 在 sulfonated porous carbon 作用下， 反应 0.75h， 以88%的产率得到S-(1-adamantyl) 4-propan-2-ylbenzenecarbothioate
  参考文献：
  名称：

  Sulfonated porous carbon catalyzed direct and efficient conversion of tertiary, allylic, and benzylic alcohols to thioesters

  摘要：

  A one-pot conversion of alcohols to thioesters using a sulfonated porous carbon (SPC) as a solid acid catalyst is reported. It was found that, when a tertiary, benzylic, or allylic alcohol was reacted with thioamides in the presence of SPC, the corresponding thioesters were produced in good to excellent yields in a short time.

  DOI：

  10.1080/17415993.2012.684204

文献信息

• One-Step Conversion of Alcohols into Thioesters
  作者：Hassan Boeini、Mehdi Mobin

  DOI：10.1055/s-0030-1259028

  日期：2010.12

  A one-step conversion of alcohols into thioesters under solvent-free conditions is reported. The alcohols were reacted with primary thioamides in the presence of p-toluenesulfonic acid under solvent-free conditions to produce the corresponding thioesters in good to excellent yields.

  报道了在无溶剂条件下将醇一步转化为硫酯。醇与伯硫代酰胺在对甲苯磺酸存在下在无溶剂条件下反应，以良好至极好的产率制备相应的硫酯。