2-propargyl 4-O-acetyl-2,3,6-trideoxy-α-L-erythrohexopyranoside | 1208260-37-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-propargyl 4-O-acetyl-2,3,6-trideoxy-α-L-erythrohexopyranoside
• CAS: 1208260-37-0
• 化学式: C₁₁H₁₆O₄
• 分子量: 212.246
• InChiKey: AGMOSOADJSIPNK-JMJZKYOTSA-N

反应信息

• 作为产物：
  描述：

  methyl 4-O-acetyl-2,3,6-trideoxy-L-erythro-hexopyranoside 、 2-丙炔-1-醇 在 三氟化硼乙醚 作用下， 反应 5.17h， 生成 2-propargyl 4-O-acetyl-2,3,6-trideoxy-β-L-erythro-hexopyranoside 、 2-propargyl 4-O-acetyl-2,3,6-trideoxy-α-L-erythrohexopyranoside
  参考文献：
  名称：

  Synthesis and antibacterial activity of aminosugar-functionalized intercalating agents

  摘要：

  A series of previously reported amino sugar-functionalized intercalating agents, 3-14, were evaluated in two antibacterial assays (paper disk diffusion and 96-well microdilution) against Bacillus atrophaeus, ATCC 9372 and Escherichia coli, ATCC 47076. Although none of the compounds were active against this E. coli strain, several showed activity against B. atrophaeus. In anticipation of the need for larger amounts of these compounds for future structure-activity relationship studies, improved routes to 11-14 were developed. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2009.10.010