| 1314035-82-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• CAS: 1314035-82-9
• 化学式: C₅₃H₃₆N₄O₃Zn
• 分子量: 842.284
• InChiKey: OQHJTMKVHWHGBU-MPPVZAFRSA-M

反应信息

• 作为产物：
  描述：

  在 水 、 sodium hydroxide 、 盐酸 、 zinc(II) acetate dihydrate 作用下， 以 四氢呋喃 、 甲醇 、 氯仿 、 水 为溶剂， 反应 6.0h， 以83.5 mg的产率得到
  参考文献：
  名称：

  Appending zinc tetraphenylporphyrin with an amine receptor at β-pyrrolic carbon for designing a selective histamine chemosensor

  摘要：

  Adopting the rarely used beta-functionalisation strategy in porphyrin-based sensor design, an amine receptive site is appended onto the Zinc(II) porphyrin molecular framework affording a ditopic chemosensor 4. The assembled chemosensor interacts selectively with histamine in toluene via a 'two-site' binding mode. Association constant of the complex evaluated from the respective UV-vis spectra is found to be (2.32 +/- 0.57) x 10(6), which is approximately 4-fold greater than those complexes derived from 4 and nicotine/histidine. On the basis of a combined spectroscopic method and molecular modelling, the binding model of the porphyrin host and biogenic guest molecules is established. Our results clearly demonstrate the viability of the design and development of the porphyrin-based chemosensor by appending a receptor at the beta-pyrrolic carbon of the porphyrin scaffold.

  DOI：

  10.1080/10610270903377349