(3-{7-[3-(pyrrolidine-1-carbonyl)-phenyl]-1H-indol-4-yl}-phenyl)-pyrrolidin-1-yl-methanone | 1312544-35-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: (3-{7-[3-(pyrrolidine-1-carbonyl)-phenyl]-1H-indol-4-yl}-phenyl)-pyrrolidin-1-yl-methanone
• 英文别名: [3-[7-[3-(pyrrolidine-1-carbonyl)phenyl]-1H-indol-4-yl]phenyl]-pyrrolidin-1-ylmethanone
• CAS: 1312544-35-6
• 化学式: C₃₀H₂₉N₃O₂
• 分子量: 463.579
• InChiKey: GDMHLQYNLKRVHL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  35
• 可旋转键数：
  4
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  56.4
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  (3-{7-[3-(pyrrolidine-1-carbonyl)-phenyl]-1H-indol-4-yl}-phenyl)-pyrrolidin-1-yl-methanone 、 四丁基碘化铵 以 四氢呋喃 为溶剂， 生成
  参考文献：
  名称：

  4,7-Diaryl indole-based fluorescent chemosensor for iodide ions

  摘要：

  Simple and selective indole based fluorescent sensors for iodide anions are reported. A series of 4,7-diaryl indole derivatives (DAIs) are designed and synthesized using Suzuki coupling. These DAIs shows significant changes in UV-vis and fluorescent intensity only with addition of iodides and not with other anions. The ability of these DAIS to function as selective iodide chemosensor is reported. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2011.04.039
• 作为产物：
  描述：

  2,5-二溴硝基苯 在 bis-triphenylphosphine-palladium(II) chloride 、 caesium carbonate 作用下， 以 四氢呋喃 、 水 、 N,N-二甲基甲酰胺 为溶剂， 反应 16.0h， 生成 (3-{7-[3-(pyrrolidine-1-carbonyl)-phenyl]-1H-indol-4-yl}-phenyl)-pyrrolidin-1-yl-methanone
  参考文献：
  名称：

  4,7-Diaryl indole-based fluorescent chemosensor for iodide ions

  摘要：

  Simple and selective indole based fluorescent sensors for iodide anions are reported. A series of 4,7-diaryl indole derivatives (DAIs) are designed and synthesized using Suzuki coupling. These DAIs shows significant changes in UV-vis and fluorescent intensity only with addition of iodides and not with other anions. The ability of these DAIS to function as selective iodide chemosensor is reported. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2011.04.039

文献信息

• 4,7-Diaryl indole-based fluorescent chemosensor for iodide ions
  作者：Krishnaswamy R. Rathikrishnan、Vellore K. Indirapriyadharshini、Seeram Ramakrishna、Rajendiran Murugan

  DOI：10.1016/j.tet.2011.04.039

  日期：2011.6

  Simple and selective indole based fluorescent sensors for iodide anions are reported. A series of 4,7-diaryl indole derivatives (DAIs) are designed and synthesized using Suzuki coupling. These DAIs shows significant changes in UV-vis and fluorescent intensity only with addition of iodides and not with other anions. The ability of these DAIS to function as selective iodide chemosensor is reported. (C) 2011 Elsevier Ltd. All rights reserved.