7-octyl 2-acetamido-4-O-(2-O-(α-L-fucopyranosyl)-β-D-galactopyranosyl)-2-deoxy-β-D-glucopyranoside | 1258298-84-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 7-octyl 2-acetamido-4-O-(2-O-(α-L-fucopyranosyl)-β-D-galactopyranosyl)-2-deoxy-β-D-glucopyranoside
• CAS: 1258298-84-8
• 化学式: C₂₈H₅₁NO₁₅
• 分子量: 641.711
• InChiKey: VPNQKTBNVCIPEF-SKKHWUFESA-N

反应信息

• 作为产物：
  描述：

  7-octen-1-yl 2-acetamido-2-deoxy-4-O-(2-O-(α-L-fucopyranosyl)-β-D-galactopyranosyl)-β-D-glucopyranoside 在 palladium 10% on activated carbon 、 氢气 作用下， 以 甲醇 为溶剂， 反应 24.0h， 以96%的产率得到7-octyl 2-acetamido-4-O-(2-O-(α-L-fucopyranosyl)-β-D-galactopyranosyl)-2-deoxy-β-D-glucopyranoside
  参考文献：
  名称：

  Synthesis of ABO histo-blood group type I and II antigens

  摘要：

  The ABO histo-blood group system is one of the most clinically important antigen families. As part of our overall goal to prepare the entire set of the A, B and H type I-VI antigens for a range of biochemical investigations, we report herein the synthesis of the type land II antigens with a 7-octen-1-yl aglycone. This linker was chosen to facilitate not only the future conjugation of the antigens to a protein or solid support but also the synthesis of the H type I and II octyl glycosides for enzyme kinetic studies. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2010.08.012