[(2R,3R,4S,5R,6R)-2-dec-9-enoxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl] benzoate | 280742-36-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: [(2R,3R,4S,5R,6R)-2-dec-9-enoxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl] benzoate
• CAS: 280742-36-1
• 化学式: C₂₃H₃₄O₇
• 分子量: 422.519
• InChiKey: GAIPFKLLBKISBB-DLBZZEGUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  30
• 可旋转键数：
  14
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.61
• 拓扑面积：
  105
• 氢给体数：
  3
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  [(2R,3R,4S,5R,6R)-2-dec-9-enoxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl] benzoate 在 吡啶 、 4-二甲氨基吡啶 、 对甲苯磺酸 作用下， 以 吡啶 、 乙腈 为溶剂， 生成 4-[(2R,3S,4S,5R,6R)-3,5-dibenzoyloxy-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-6-dec-9-enoxyoxan-4-yl]oxy-4-oxobutanoic acid
  参考文献：
  名称：

  Application of MPEG soluble polymer support in the synthesis of oligo-phosphosaccharide fragments from the Leishmania lipophosphoglycan

  摘要：

  A polymer (MPEG) supported synthesis of the phosphorylated tetra- and hexa-saccharide fragments of the lipophosphoglycan from Leishmania has been developed using mono- and di-saccharide H-phosphonates for construction of the phosphodiester bridges. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(00)00153-2
• 作为产物：
  描述：

  [(3aS,4R,6R,7R,7aS)-6-dec-9-enoxy-2,2-dimethyl-4-(trityloxymethyl)-4,6,7,7a-tetrahydro-3aH-[1,3]dioxolo[4,5-c]pyran-7-yl] benzoate 在 溶剂黄146 作用下， 生成 [(2R,3R,4S,5R,6R)-2-dec-9-enoxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl] benzoate
  参考文献：
  名称：

  Application of MPEG soluble polymer support in the synthesis of oligo-phosphosaccharide fragments from the Leishmania lipophosphoglycan

  摘要：

  A polymer (MPEG) supported synthesis of the phosphorylated tetra- and hexa-saccharide fragments of the lipophosphoglycan from Leishmania has been developed using mono- and di-saccharide H-phosphonates for construction of the phosphodiester bridges. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(00)00153-2

文献信息

• Application of MPEG soluble polymer support in the synthesis of oligo-phosphosaccharide fragments from the Leishmania lipophosphoglycan
  作者：Andrew J Ross、Irina A Ivanova、Adrian P Higson、Andrei V Nikolaev

  DOI：10.1016/s0040-4039(00)00153-2

  日期：2000.4

  A polymer (MPEG) supported synthesis of the phosphorylated tetra- and hexa-saccharide fragments of the lipophosphoglycan from Leishmania has been developed using mono- and di-saccharide H-phosphonates for construction of the phosphodiester bridges. (C) 2000 Elsevier Science Ltd. All rights reserved.