α-D-galactopyranosyl-(1->4)-β-Δ^5,5a-carba-D-galactopyranose | 1225450-90-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: α-D-galactopyranosyl-(1->4)-β-Δ^5,5a-carba-D-galactopyranose
• CAS: 1225450-90-7
• 化学式: C₁₃H₂₂O₁₀
• 分子量: 338.312
• InChiKey: XZSBRDVVKPHKDI-COJYFQMGSA-N

反应信息

• 作为产物：
  描述：

  在 水 、 2,3-二氯-5,6-二氰基-1,4-苯醌 作用下， 以 二氯甲烷 为溶剂， 反应 40.0h， 以8.7 mg的产率得到α-D-galactopyranosyl-(1->4)-β-Δ^5,5a-carba-D-galactopyranose
  参考文献：
  名称：

  Synthesis of a trigalacturonic acid analogue mimicking the expected transition state in the glycosidases

  摘要：

  A trigalacturonic acid analogue carrying a cyclohexene framework in place of the central pyranose ring was synthesized as a molecular probe for the mechanistic investigation of endo-polygalacturonase 1 (endo-PG 1). Preliminary enzymatic studies revealed that this analogue inhibited endo-PG 1 activity by about 30% at 0.3 mM concentration. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2009.12.024