(E)-pentadec-2-en-4-one | 434313-22-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (E)-pentadec-2-en-4-one
• CAS: 434313-22-1
• 化学式: C₁₅H₂₈O
• 分子量: 224.387
• InChiKey: XYVQXRCXBOAYOF-YIXHJXPBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6
• 重原子数：
  16
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  (4RS)-1-十五碳烯-4-醇 以27%的产率得到
  参考文献：
  名称：

  LUND G. K.; HOLT S. L., J. CHEM. AND ENG. DATA, 1981, 26, NO 2, 227-229

  摘要：

  DOI：

文献信息

• METHYLKETONE SYNTHASE, PRODUCTION OF METHYLKETONES IN PLANTS AND BACTERIA
  申请人：Pichersky Eran

  公开号：US20110289632A1

  公开（公告）日：2011-11-24

  Isolated genes and amino acid sequences encode methylketone synthase 2 (MKS2) enzymes from tomato plants, including, ShMKS2 and SlMKS2. When expressed recombinantly in bacteria and other host cells, the MKS2 enzymes produce methylketones of various carbon chain lengths ranging from C 7 to C 20 from 3-ketoacyl intermediate substrates. Methylketones are known to have important roles in protecting plants against pests, and also as flavor compounds, and can be used as stockfeed in the chemical industry.

  孤立的基因和氨基酸序列编码了来自番茄植物的甲基酮合酶2（MKS2）酶，包括ShMKS2和SlMKS2。当在细菌和其他宿主细胞中重组表达MKS2酶时，这些酶会从3-酮酰中间体底物产生碳链长度从C7到C20的各种甲基酮。甲基酮已知在保护植物免受害虫的作用中起重要作用，也作为风味化合物，并可用作化工业的饲料。
• Copper-Catalyzed Enantioselective Synthesis of <i>trans</i>-1-Alkyl-2-substituted Cyclopropanes via Tandem Conjugate Addition−Intramolecular Enolate Trapping
  作者：Tim den Hartog、Alena Rudolph、Beatriz Maciá、Adriaan J. Minnaard、Ben L. Feringa

  DOI：10.1021/ja105704m

  日期：2010.10.20

  Cu-TolBINAP-catalyzed conjugate addition of Grignard reagents to 4-chloro-alpha,beta-unsaturated esters, thioesters, and ketones leads to 4-chloro-3-alkyl-substituted thioesters and ketones in up to 84% yield and up to 96% ee upon protonation of the corresponding enolates at low temperature. Tandem conjugate addition-enolate trapping, however, yields trans-1-alkyl-2-substituted cyclopropanes in up to 92% yield and up to 98% ee. The versatility of this reaction is illustrated by the formation of key intermediates for the formal syntheses of cascarillic acid and grenadamide.
• BACTERIAL PRODUCTION OF METHYL KETONES
  申请人：The Regents of the University of California

  公开号：EP2771381B1

  公开（公告）日：2017-12-06
• US3953377A
  申请人：——

  公开号：US3953377A

  公开（公告）日：1976-04-27
• US9556458B2
  申请人：——

  公开号：US9556458B2

  公开（公告）日：2017-01-31