4-(azidomethyl)-2,5-diphenyl-1,3-oxazole | 201033-47-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 4-(azidomethyl)-2,5-diphenyl-1,3-oxazole
• CAS: 201033-47-8
• 化学式: C₁₆H₁₂N₄O
• 分子量: 276.297
• InChiKey: DVIBIPPGPBJPPI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.82
• 重原子数：
  21.0
• 可旋转键数：
  4.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  74.79
• 氢给体数：
  0.0
• 氢受体数：
  3.0

反应信息

• 作为反应物：
  描述：

  4-(azidomethyl)-2,5-diphenyl-1,3-oxazole 在 palladium on activated charcoal 氢气 、 三乙胺 作用下， 以 二氯甲烷 、 乙酸乙酯 为溶剂， 生成 N-[(2,5-diphenyl-1,3-oxazol-4-yl)methyl]acetamide
  参考文献：
  名称：

  Synthesis and scintillating efficiencies of 4-functionalised-2,5-diphenyloxazoles

  摘要：

  A series of 4-functionalised-2,5-diphenyloxazoles has been synthesised. Each member of the series has been assessed for the ability to scintillate in the presence of ionising radiation. The scintillation counting efficiency of each member of the series has been determined relative to 2,5-diphenyloxazole, a widely used scintillant molecule. (C) 1997 Published by Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4039(97)10435-x
• 作为产物：
  描述：

  4-bromomethyl-2,5-diphenyloxazole 在 sodium azide 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 以97%的产率得到4-(azidomethyl)-2,5-diphenyl-1,3-oxazole
  参考文献：
  名称：

  Synthesis and scintillating efficiencies of 4-functionalised-2,5-diphenyloxazoles

  摘要：

  A series of 4-functionalised-2,5-diphenyloxazoles has been synthesised. Each member of the series has been assessed for the ability to scintillate in the presence of ionising radiation. The scintillation counting efficiency of each member of the series has been determined relative to 2,5-diphenyloxazole, a widely used scintillant molecule. (C) 1997 Published by Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4039(97)10435-x