2t,6t-Dichlor-cyclohexan-1r-ol | 28007-62-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2t,6t-Dichlor-cyclohexan-1r-ol
• CAS: 28007-62-7
• 化学式: C₆H₁₀Cl₂O
• 分子量: 169.051
• InChiKey: FBKOESDSJIAOCA-FMCRUOTFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.75
• 重原子数：
  9.0
• 可旋转键数：
  0.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  20.23
• 氢给体数：
  1.0
• 氢受体数：
  1.0

反应信息

• 作为产物：
  描述：

  trans-2-chloro-7-oxabicyclo<4.1.0>heptane 在 盐酸 作用下， 生成 2t,6t-Dichlor-cyclohexan-1r-ol
  参考文献：
  名称：

  Radical reactions of epoxides. Chlorine-atom abstraction from .alpha.- and .beta.-chloro epoxides by the triphenyltin radical

  摘要：

  The four isomers of chloroepoxypropane have been prepared, and their relative reactivities with triphenyltin hydride have been determined. The three alpha-chloroepoxypropanes react at a much slower rate than does epichlorohydrin, the only beta-chloro epoxide of the four. The nature of the increased reactivity for the beta-chloro epoxides has been investigated by studying two pair of diastereomeric beta-chloro epoxides, and a single acyclic beta-chloro ether. The results are discussed in terms of the inductive, resonance, and stereoelectronic effects of the epoxide.

  DOI：

  10.1021/jo00029a011