4-hydroxy-3-[(E)-3-(1-ethyl-1,2,3,4-tetrahydroquinoline-6-yl)prop-2-enoyl]-1-methylquinone-2 | 1245559-39-0

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 直链 1,3-二芳基丙烷
• 英文名称: 4-hydroxy-3-[(E)-3-(1-ethyl-1,2,3,4-tetrahydroquinoline-6-yl)prop-2-enoyl]-1-methylquinone-2
• 英文别名: 4-hydroxy-3-[(E)-3-(1-ethyl-1,2,3,4-tetrahydroquinoline-6-yl)prop-2-enoyl]-1-methyl-1H-quinolin-2-one
• CAS: 1245559-39-0
• 化学式: C₂₄H₂₄N₂O₃
• 分子量: 388.466
• InChiKey: NPXCKONNEXSKQT-ACCUITESSA-N

反应信息

• 作为产物：
  描述：

  3-[(E)-3-(1-ethyl-1,2,3,4-tetrahydroquinoline-6-yl)propyl-2-enoyl]-4-difluoroboronoxy-1-methylquinone-2 在 水 、 sodium carbonate 作用下， 以 乙醇 为溶剂， 以75%的产率得到4-hydroxy-3-[(E)-3-(1-ethyl-1,2,3,4-tetrahydroquinoline-6-yl)prop-2-enoyl]-1-methylquinone-2
  参考文献：
  名称：

  2-Quinolone and coumarin polymethines for the detection of proteins using fluorescence

  摘要：

  A series of novel, polymethine chalcone dye - 2-quinolone derivatives and their boron difluoride complexes were synthesized. The spectral-luminescence properties of a series of 2-quinolones and their coumarin analogues were characterized in the presence of a denaturing agent (sodium dodecyl sulfate), native bovine serum albumin as well as a combination of serum albumin and sodium dodecyl sulfate. A study of the influence of the BF(2)-ether group on the sensitivity of the polymethine dyes to proteins revealed that three of the dyes, namely two hydroxyquinoline dyes containing a 4-diethylamino-2-hydroxyphenyl substituent and a coumarine dye that contained an indolenine substituent, displayed high emission and bright fluorescence (quantum yield <= 0.27) and thus offer promise for use in protein detection. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.dyepig.2009.07.009