Bn(-2)[Bn(-3)][Bn(-5)]D-Araf(b1-5)[Bn(-2)][Bn(-3)]a-D-Araf1Ac | 1252031-95-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Bn(-2)[Bn(-3)][Bn(-5)]D-Araf(b1-5)[Bn(-2)][Bn(-3)]a-D-Araf1Ac
• 英文别名: [(2R,3S,4R,5R)-5-[[(2R,3S,4R,5R)-3,4-bis(phenylmethoxy)-5-(phenylmethoxymethyl)oxolan-2-yl]oxymethyl]-3,4-bis(phenylmethoxy)oxolan-2-yl] acetate
• CAS: 1252031-95-0
• 化学式: C₄₇H₅₀O₁₀
• 分子量: 774.908
• InChiKey: VLJFGJNJONMHSC-DGPVJTTPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.7
• 重原子数：
  57
• 可旋转键数：
  21
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.34
• 拓扑面积：
  100
• 氢给体数：
  0
• 氢受体数：
  10

反应信息

• 作为产物：
  描述：

  2',3',5'-tri-O-benzyl-α,β-D-arabinofuranosyl-(1->5)-2,3-di-O-benzyl-α,β-D-arabinofuranose 、 乙酸酐 在 吡啶 作用下， 生成 Bn(-2)[Bn(-3)][Bn(-5)]D-Araf(b1-5)[Bn(-2)][Bn(-3)]a-D-Araf1Ac 、
  参考文献：
  名称：

  Synthesis of partially benzylated arabinofuranosides, NMR analysis, and application to oligosaccharide synthesis

  摘要：

  The preparation and NMR analysis of 2,3-di-O-benzyl arabinofuranosides have been described. In DMSO-d(6), the sugar adopts a conformation in which the hydroxyl groups are in an equatorial position; the equilibrium composition is determined by steric factors. In CDCl3, the sugar adopts a conformation in which the intramolecular hydrogen bonding plays an important role in determining the equilibrium composition. The use of 2,3-di-O-benzyl arabinose in the synthesis of oligoarabinofuranosides enabled the synthesis of alpha- or beta-linked furanosides. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2010.06.033