2-(pyridin-4-yloxy)benzaldehyde | 33399-37-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-(pyridin-4-yloxy)benzaldehyde
• 英文别名: 4-(2-Formyl-phenoxy)-pyridin；2-pyridin-4-yloxybenzaldehyde
• CAS: 33399-37-0
• 化学式: C₁₂H₉NO₂
• 分子量: 199.209
• InChiKey: ILYIBYDYZFJRRA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  39.2
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  (2-Pyridin-4-yloxyphenyl)methanol 在 草酰氯 、 三乙胺 作用下， 以 二氯甲烷 、 二甲基亚砜 为溶剂， 生成 2-(pyridin-4-yloxy)benzaldehyde
  参考文献：
  名称：

  OREXIN RECEPTOR AGONISTS

  摘要：

  The present invention is directed to compounds of Formula I which are agonists of orexin receptors. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which orexin receptors are involved.

  公开号：

  WO2024107615A1

文献信息

• N-(2-ARYLETHYL)BENZYLAMINES AS ANTAGONISTS OF THE 5-HT6 RECEPTOR
  申请人：Chen Zhaogen

  公开号：US20090306110A1

  公开（公告）日：2009-12-10

  The present invention provides compounds of formula (I), which are antagonists of the 5-HT 6 receptor.

  本发明提供了式（I）的化合物，它们是5-HT6受体的拮抗剂。
• US8044090B2
  申请人：——

  公开号：US8044090B2

  公开（公告）日：2011-10-25