3-Piperidino-carbostyril | 6854-12-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 3-Piperidino-carbostyril
• 英文别名: 3-piperidin-1-yl-1H-quinolin-2-one；1-Piperidyl-Chinolon；3-piperidin-1-yl-1H-quinolin-2-one
• CAS: 6854-12-2
• 化学式: C₁₄H₁₆N₂O
• 分子量: 228.294
• InChiKey: ZMZNUZNJHOFDOZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  17
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  32.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• CHIRAL BROAD-SPECTRUM ANTIBACTERIAL 7-SUBSTITUTED PIPERIDINO-QUINOLONE CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND COMPOSITIONS
  申请人：Wockhardt Limited

  公开号：EP1392677A2

  公开（公告）日：2004-03-03
• NEW GENERATION TRIPLE-TARGETING, CHIRAL, BROAD-SPECTRUM ANTIMICROBIAL 7-SUBSTITUTED PIPERIDINO-QUINOLONE CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION, COMPOSITIONS AND USE AS MEDICAMENTS
  申请人：Wockhardt Limited

  公开号：EP1453824A1

  公开（公告）日：2004-09-08
• [EN] CHIRAL, BROAD-SPECTRUM ANTIBACTERIAL 7-SUBSTITUTED PIPERIDINO-QUINOLONE CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND COMPOSITIONS<br/>[FR] NOUVELLE GENERATION DE DERIVES CHIRAUX D'ACIDE PIPERIDINO-QUINOLONE CARBOXYLIQUE SUBSTITUE EN 7, A TRIPLE CIBLE ET A LARGE SPECTRE ANTIMICROBIEN, LEUR PREPARATION, LEURS COMPOSITIONS ET LEUR UTILISATION COMME MEDICAMENTS
  申请人：DE SOUZA NOEL J

  公开号：WO2002085886A2

  公开（公告）日：2002-10-31

  This invention relates to new generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, to their optical isomers, diastereomers or enantiomers, as well as pharmaceutically acceptable salts, hydrates, prodrugs, polymorphs and pseudopolymorphs thereof, to their preparation, to their compositions and to their use.
• [EN] NEW GENERATION TRIPLE-TARGETING, CHIRAL, BROAD-SPECTRUM ANTIMICROBIAL 7-SUBSTITUTED PIPERIDINO-QUINOLONE CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION, COMPOSITIONS AND USE AS MEDICAMENTS<br/>[FR] NOUVEAUX DERIVES D'ACIDE PIPERIDINO-QUINOLONE CARBOXYLIQUE SUBSTITUE EN POSITION 7, CHIRAUX, A ACTION ANTIMICROBIENNE A LARGE SPECTRE ET CIBLAGE TRIPLE, PREPARATION, COMPOSITIONS CONTENANT CES DERIVES ET LEUR UTILISATION EN TANT QUE MEDICAMENTS
  申请人：DE SOUZA NOEL J

  公开号：WO2003050107A1

  公开（公告）日：2003-06-19

  This invention relates to new generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, to their optical isomers, diastereomers or enantiomers, as well as pharmaceutically acceptable salts, hydrates, prodrugs, polymorphs and pseudopolymorphs thereof, to their preparation, to their compositions and to their use.