(2R,3R,4S,5R,6R)-2-[(1-dodecyltriazol-4-yl)methoxy]-6-(hydroxymethyl)oxane-3,4,5-triol | 1190202-90-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2R,3R,4S,5R,6R)-2-[(1-dodecyltriazol-4-yl)methoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
• CAS: 1190202-90-4
• 化学式: C₂₁H₃₉N₃O₆
• 分子量: 429.557
• InChiKey: DOKJWQGTAXJACB-XDWAVFMPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  30
• 可旋转键数：
  15
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  130
• 氢给体数：
  4
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  1-叠氮十二烷 、 1-propynyl-β-D-galactopyranoside 在 copper diacetate 、 sodium ascorbate 作用下， 以 水 、 叔丁醇 为溶剂， 生成 (2R,3R,4S,5R,6R)-2-[(1-dodecyltriazol-4-yl)methoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
  参考文献：
  名称：

  Expanding the application scope of glycosidases using click chemistry

  摘要：

  Glycosidase-mediated glycosylation of alkynyl alcohols and azide-containing alcohols was followed by a click reaction, affording various types of triazole glycosides. The activities of triazole glycosides detected in Subsequent bioassays show that this procedure is a feasible approach to the development of anti-fungal drugs. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2009.11.044

文献信息

• Expanding the application scope of glycosidases using click chemistry
  作者：Wen-Ya Lu、Xing-Wen Sun、Chen Zhu、Jian-He Xu、Guo-Qiang Lin

  DOI：10.1016/j.tet.2009.11.044

  日期：2010.1

  Glycosidase-mediated glycosylation of alkynyl alcohols and azide-containing alcohols was followed by a click reaction, affording various types of triazole glycosides. The activities of triazole glycosides detected in Subsequent bioassays show that this procedure is a feasible approach to the development of anti-fungal drugs. (C) 2009 Elsevier Ltd. All rights reserved.