p-azidophenyl α-D-glucopyranoside | 134507-63-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: p-azidophenyl α-D-glucopyranoside
• 英文别名: p-Azidophenyl alpha-D-glucopyranoside；(2R,3R,4S,5S,6R)-2-(4-azidophenoxy)-6-(hydroxymethyl)oxane-3,4,5-triol
• CAS: 134507-63-4
• 化学式: C₁₂H₁₅N₃O₆
• 分子量: 297.268
• InChiKey: XNEQKXXRWVEJND-ZIQFBCGOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  114
• 氢给体数：
  4
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  对硝基苯-α-D-葡萄糖吡喃苷 在 sodium dithionite 作用下， 以77%的产率得到p-azidophenyl α-D-glucopyranoside
  参考文献：
  名称：

  Photolabeling of dextransucrase from Streptococcus sanguis with p-azidophenyl α-d-glucopyranoside

  摘要：

  Dextransucrase from Streptococcus sanguis ATCC 10558 was photolabeled using p-azidophenyl alpha-D-glucopyranoside with an apparent rate constant of inactivation of 1.40 min-1. The dissociation constant for this compound, which acts as an acceptor molecule in the enzymatic reaction, is 90-mu-M. Apparently two acceptor binding sites exist on dextransucrase as shown by (i.) photolabeling the enzyme with p-azidophenyl-alpha-D-[5,6-H-3]glucopyranoside and (ii.) fluorescence titration experiments.

  DOI：

  10.1016/0008-6215(91)80101-r