| 1239956-29-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 1239956-29-6
• 化学式: C₂₇H₂₈N₆O₈
• 分子量: 564.555
• InChiKey: MVZVTQIZLIRUHO-YMGHBJPRSA-N

反应信息

• 作为反应物：
  描述：

  、 2,2-二甲氧基丙烷 在 BSA 作用下， 以 丙酮 为溶剂， 以37%的产率得到1-[(3aR,4R,6R,6aR)-6-[(1S,2R)-2-azido-3-(2,3-dihydroindol-1-yl)-1-hydroxy-3-oxopropyl]-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl]-3-[(4-methoxyphenyl)methyl]pyrimidine-2,4-dione
  参考文献：
  名称：

  Efficient synthesis of the core structure of muraymycin and caprazamycin nucleoside antibiotics based on a stereochemically revised sulfur ylide reaction

  摘要：

  The reaction of protected uridine 5'-aldehydes with sulfur ylides has been reinvestigated Further transformation of the resulting epoxide product provided a compound of which a single crystal for X-ray diffraction was obtained. As a consequence from the elucidated structure, the stereochemical configuration of the epoxide furnished by the sulfur ylide reaction was revised. Based on these results, an efficient synthesis of the core structure of the naturally occurring muraymycin and caprazamycin nucleoside antibiotics was developed. (C) 2010 Elsevier Ltd. All rights reserved

  DOI：

  10.1016/j.tetasy.2010.03.037
• 作为产物：
  描述：

  在 乙酰氯 作用下， 以 甲醇 为溶剂， 以90%的产率得到
  参考文献：
  名称：

  Efficient synthesis of the core structure of muraymycin and caprazamycin nucleoside antibiotics based on a stereochemically revised sulfur ylide reaction

  摘要：

  The reaction of protected uridine 5'-aldehydes with sulfur ylides has been reinvestigated Further transformation of the resulting epoxide product provided a compound of which a single crystal for X-ray diffraction was obtained. As a consequence from the elucidated structure, the stereochemical configuration of the epoxide furnished by the sulfur ylide reaction was revised. Based on these results, an efficient synthesis of the core structure of the naturally occurring muraymycin and caprazamycin nucleoside antibiotics was developed. (C) 2010 Elsevier Ltd. All rights reserved

  DOI：

  10.1016/j.tetasy.2010.03.037