2,2-bis-(4-dimethylamino-phenyl)-1,2-diphenyl-ethanone | 14500-39-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 三苯基化合物
• 英文名称: 2,2-bis-(4-dimethylamino-phenyl)-1,2-diphenyl-ethanone
• 英文别名: 2,2-Bis-(4-dimethylamino-phenyl)-1,2-diphenyl-aethanon；4.4'-Bis-dimethylamino-β-benzpinakolin；4.4'-Bis-dimethylamino-α-benzoyl-triphenylmethan；α-Phenyl-α,α-bis--acetophenon；1,2-Diphenyl-2,2-bis-<4-dimethylamino-phenyl>-aethan-1-on；2,2-Bis[4-(dimethylamino)phenyl]-1,2-diphenylethanone
• CAS: 14500-39-1
• 化学式: C₃₀H₃₀N₂O
• 分子量: 434.581
• InChiKey: JZXSCXHAVTVUHP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.6
• 重原子数：
  33
• 可旋转键数：
  7
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  23.6
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2,2-bis-(4-dimethylamino-phenyl)-1,2-diphenyl-ethanone 、 alkaline earth salt of/the/ methylsulfuric acid 生成 隐色孔雀绿 、 苯甲酸
  参考文献：
  名称：

  Madelung; Oberwegner, Chemische Berichte, 1927, vol. 60, p. 2484

  摘要：

  DOI：
• 作为产物：
  描述：

  对二甲氨基二苯甲酮 在 乙醇 、 溶剂黄146 、 锌 作用下， 生成 2,2-bis-(4-dimethylamino-phenyl)-1,2-diphenyl-ethanone
  参考文献：
  名称：

  Binding of FITC-labelled lectins to the gastrointestinal epithelium of the rat

  摘要：

  Biotechnology uses lectin genes to transfect into crop plants for protection against insects and nematodes. On the other hand, the information is limited on lectin-binding properties of cells in the gastrointestinal tract. Therefore, binding of a panel of FITC-labelled plant lectins to gastrointestinal cells of the rat was studied. In the stomach, cytoplasmic staining of parietal cells by PHA appeared to be due to glycoproteins attached to the tubulovesicles. PNA also stained the parietal cells, but only in the isthmus and neck regions, reacting with desialylated glycoproteins. WGA bound to the mucous neck cells with higher affinity than to the surface and foveolar mucous cells. The mucous cells were also stained by SNA-I, UEA-I and, less intensively, by LCA. Chief cells did not show detectable reaction with any of the applied lectins. Binding of PHA to gastric cells showed differences when compared with the results of in vivostudies. Small intestinal brush border was stained with UEA-I and SNA-I, the latter lectin also strongly stained the surface of small intestinal crypts. Both lectins reacted with the mucus of goblet cells. In the large intestine UEA-I and SNA-I stained the goblet cells at the base and upper part of the crypts, respectively. Accordingly, we provided evidences for the unique lectin-binding phenotype of the various segments of the gastrointestinal tract.

  DOI：

  10.1007/bf03032370