| 1350638-44-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 1350638-44-6
• 化学式: C₂₂H₃₀O₇S
• 分子量: 438.542
• InChiKey: KLMGLZSSQNTSSQ-CTWRKMMKSA-N

反应信息

• 作为产物：
  描述：

  在 甲醇 、 sodium methylate 作用下， 生成
  参考文献：
  名称：

  Rapid Chemo-Enzymatic Synthesis of Peracetylated GlcNAcβ3Galβ-Aglycones

  摘要：

  The inhibition of sialyl Lewis X can prevent unwanted cellular extravasation that is associated with inflammatory diseases and tumor metastasis. Described is an efficient methodology to prepare peracetylated GlcNAc beta 3Gal-aglycone disaccharides subsequently used as metabolic decoys to inhibit sialyl Lewis X expression. Four glycosides were synthesized from one single parent disaccharide that in turn was prepared by large-scale enzymatic synthesis. The procedure avoids lengthy and inefficient synthetic steps to afford the desired disaccharides quickly with good overall yields.

  DOI：

  10.1080/07328303.2011.617023