pentaethoxyethane | 58995-69-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: pentaethoxyethane
• 英文别名: diethoxy-orthoacetic acid triethyl ester；Diaethoxy-orthoessigsaeure-triaethylester；1,1,1,2,2-Pentaethoxyethane
• CAS: 58995-69-0
• 化学式: C₁₂H₂₆O₅
• 分子量: 250.335
• InChiKey: KKWBHRJMNBQJSN-UHFFFAOYSA-N

物化性质

• 沸点：
  170 °C
• 密度：
  0.967±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  17
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  46.2
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  pentaethoxyethane 在 ethyl sodium 、 Petroleum ether 作用下， 生成 四乙氧基乙烯
  参考文献：
  名称：

  Clinical Applications of Serum Placental Protein 14 (PP14) Measurement in the IVF-ET Cycle

  摘要：

  AbstractObjective: Placental protein 14 (PP14) is known to be one of the endometrial proteins that reflect endometrial functioning throughout the menstrual cycle. In this study, we examined PP14 as a marker for human endometrial receptivity in order to predict the outcome of in vitro fertilization and the embryo‐transfer (IVF‐ET) cycle.Patients and Methods: The subjects were 72 women who had 96 IVF‐ET cycles and who were examined at Tokyo Medical University Hospital during the period of January 1998 to June 1998 because of mechanical or unexplained infertility for a duration of at least 2 years. Serum samples were collected from all patients during treatment cycles, and serum PPI4 concentrations were measured by a newly established enzyme‐linked immunosorbent assay (ELISA).Results: In the pregnant group, serum PP14 concentrations were markedly increased after ET, and a significant difference between the pregnant group and the nonpregnant group was observed 8 days following ET (p < 0.01). PP14 concentrations were higher in patients with endometria that exhibited homogenous patterns and that were more than 7 mm thicker than in other patients, as determined by ultrasound on the day of oocyte collection (p < 0.005). The pregnancy rates of patients with homogeneous patterns were lower than those of patients showing a trilaminar pattern. No pregnancies were observed when serum PP14 concentrations were greater than 6.85 U/l on the day of oocyte collection.Conclusion: PP14 might be a useful marker for human endometrial receptivity to predict the outcome of IVF‐ET cycles.

  DOI：

  10.1111/j.1447-0756.2000.tb01325.x
• 作为产物：
  描述：

  原甲酸三乙酯 在 三氟化硼乙醚 、 N,N-二异丙基乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 0.25h， 生成 pentaethoxyethane
  参考文献：
  名称：

  Procedure for diethoxymethylation of ketones

  摘要：

  DOI：

  10.1021/jo00325a023

文献信息

• Scheibler; Beiser; Krabbe, Journal fur praktische Chemie (Leipzig 1954), 1932, vol. <2> 133, p. 133,138, 145
  作者：Scheibler、Beiser、Krabbe

  DOI：——

  日期：——
• MOCK W. L.; TSOU H.-R., J. ORG. CHEM., 1981, 46, NO 12, 2557-2561
  作者：MOCK W. L.、 TSOU H.-R.

  DOI：——

  日期：——