8-Bromcordycepin | 117213-20-4

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 嘌呤核苷
• 英文名称: 8-Bromcordycepin
• 英文别名: 8-bromo-3'-deoxy-adenosine；(2R,3R,5S)-2-(6-amino-8-bromopurin-9-yl)-5-(hydroxymethyl)oxolan-3-ol
• CAS: 117213-20-4
• 化学式: C₁₀H₁₂BrN₅O₃
• 分子量: 330.141
• InChiKey: AWLDLDDWZNZCJL-OBXARNEKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.2
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  119
• 氢给体数：
  3
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  8-Bromcordycepin 、 叠氮化钠 生成 (2R,3R,5S)-2-(6-amino-8-azidopurin-9-yl)-5-(hydroxymethyl)oxolan-3-ol
  参考文献：
  名称：

  SAJTO, MINORU;NASU, AYAKO;YAMATSUGI, NOBUYUKI;OSITA, KATSUNORI;KATO, MOTO+

  摘要：

  DOI：
• 作为产物：
  描述：

  虫草素 、 溴 生成 8-Bromcordycepin
  参考文献：
  名称：

  SAJTO, MINORU;NASU, AYAKO;YAMATSUGI, NOBUYUKI;OSITA, KATSUNORI;KATO, MOTO+

  摘要：

  DOI：

文献信息

• METHOD OF ANALYZING PROBE SUPPORT BY USING FLYING TIME SECONDARY ION MASS SPECTROMETRY
  申请人：CANON KABUSHIKI KAISHA

  公开号：EP1519189A1

  公开（公告）日：2005-03-30

  A method of analyzing a measuring sample is provided which is capable of accurately analyzing the state of a probe disposed on a carrier and formation/unformation of a hybrid between the probe and a target nucleic acid, for example, imaging of the disposing locations and quantitative analysis thereof. The state of a nucleic acid probe formed in a measuring sample obtained by reacting a sample with a probe carrier or formation/unformation of a hybrid between the probe and a target nucleic acid is detected by measurement by the Time-of-Flight Secondary Mass Spectroscopy while being labeled with a marker substance capable of generating fragment ions that are not generated by fragmentation of the probe or the target substance.

  本发明提供了一种分析测量样品的方法，该方法能够准确分析设置在载体上的探针的状态以及探针与目标核酸之间杂交体的形成/未形成，例如，对设置位置进行成像和定量分析。 通过与探针载体反应而获得的测量样品中形成的核酸探针的状态，或探针与目标核酸之间杂交体的形成/未形成，可通过飞行时间二次质谱仪进行测量检测，同时标记能够产生碎片离子的标记物质，而这些碎片离子不是由探针或目标物质的碎片产生的。
• Methods for enhancing the expression of a protein of interest by recombinant host cells
  申请人：——

  公开号：US20020019049A1

  公开（公告）日：2002-02-14

  The increased use of nucleotide sequence data mining techniques has amplified the demand for efficient methods of producing recombinant proteins in eukaryotic cells. A strategy is provided for enhancing the synthesis of recombinant amino acid sequences by polymerizing expression cassettes in vitro before producing recombinant hosts.

  随着核苷酸序列数据挖掘技术的使用日益广泛，对在真核细胞中生产重组蛋白质的高效方法的需求也在不断增加。本文提供了一种在体外聚合表达盒，然后再生产重组宿主，从而提高重组氨基酸序列合成效率的策略。
• Method of analyzing probe carrier using time-of-flight secondary ion mass spectrometry
  申请人：——

  公开号：US20040137491A1

  公开（公告）日：2004-07-15

  A method of analyzing a measuring sample is provided which is capable of accurately analyzing the state of a probe disposed on a carrier and formation/unformation of a hybrid between the probe and a target nucleic acid, for example, imaging of the disposing locations and quantitative analysis thereof. The state of a nucleic acid probe formed in a measuring sample obtained by reacting a sample with a probe carrier or formation/unformation of a hybrid between the probe and a target nucleic acid is detected by measurement by the Time-of-Flight Secondary Mass Spectroscopy while being labeled with a marker substance capable of generating fragment ions that are not generated by fragmentation of the probe or the target substance.

  本发明提供了一种分析测量样品的方法，该方法能够准确分析设置在载体上的探针的状态以及探针与目标核酸之间杂交体的形成/未形成，例如，对设置位置进行成像和定量分析。 通过与探针载体反应而获得的测量样品中形成的核酸探针的状态，或探针与目标核酸之间杂交体的形成/未形成，可通过飞行时间二次质谱仪进行测量检测，同时标记能够产生碎片离子的标记物质，而这些碎片离子不是由探针或目标物质的碎片产生的。
• IKEHDA, TAKAO
  作者：IKEHDA, TAKAO

  DOI：——

  日期：——
• METHODS FOR ENHANCING THE EXPRESSION OF A PROTEIN OF INTEREST BY RECOMBINANT HOST CELLS
  申请人：ZymoGenetics, Inc.

  公开号：EP1276881B1

  公开（公告）日：2006-02-22