(3aS,8aS)-7-(2-hydroxyethyl)-2,2-dimethyltetrahydro[1,3]dioxolo[3,4-e][1,3]oxazepin-6(7H)-one | 1262323-77-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (3aS,8aS)-7-(2-hydroxyethyl)-2,2-dimethyltetrahydro[1,3]dioxolo[3,4-e][1,3]oxazepin-6(7H)-one
• CAS: 1262323-77-2
• 化学式: C₁₀H₁₇NO₅
• 分子量: 231.249
• InChiKey: KXJYMEBNTYVSCI-YUMQZZPRSA-N

反应信息

• 作为产物：
  描述：

  benzyl ((4S,5S)-5-((tert-butyldimethylsilyloxy)methyl)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl(2-hydroxyethyl)carbamate 在 四丁基氟化铵 作用下， 以 四氢呋喃 为溶剂， 反应 3.0h， 以85%的产率得到(3aS,8aS)-7-(2-hydroxyethyl)-2,2-dimethyltetrahydro[1,3]dioxolo[3,4-e][1,3]oxazepin-6(7H)-one
  参考文献：
  名称：

  Proline catalyzed direct diastereoselective 6-enolexo aldolization: toward the synthesis of the imino sugar DNJ

  摘要：

  A L-proline catalyzed direct diastereoselective 6-enolexo aldolization reaction of differentiating dialdehydes derived from tartaric acid is presented This organocatalytic approach provides high levels of synselectivity (dr > 10 1) with the stereocontrolled C-C bond formation between C4 and C5 intramolecularly which can serve to synthesize Imino-sugar skeleton quickly (C) 2010 Elsevier Ltd All rights reserved

  DOI：

  10.1016/j.tetasy.2010.10.024