1-(4-methoxyphenyl)-3-(phenylthio)-3-(thiophen-2-yl)propan-1-one | 1373122-03-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-(4-methoxyphenyl)-3-(phenylthio)-3-(thiophen-2-yl)propan-1-one
• CAS: 1373122-03-2
• 化学式: C₂₀H₁₈O₂S₂
• 分子量: 354.494
• InChiKey: IXRFGMSLGHMASS-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  苯硫酚 、 1-(4-methoxyphenyl)-3-(thiophen-2-yl)prop-2-en-1-one 在 碘 作用下， 以 二氯甲烷 为溶剂， 反应 3.0h， 以91%的产率得到1-(4-methoxyphenyl)-3-(phenylthio)-3-(thiophen-2-yl)propan-1-one
  参考文献：
  名称：

  Synthesis and Screening Antimicrobial Activities of Novel 1,3-Diaryl-3- (Phenylthio)Propan-1-One Derivatives

  摘要：

  In this study, a series of novel beta-mercapto carbonyl derivatives (3a-j) was prepared by addition of thiophenol (2) to chalcones (1a-j) in the presence of catalytic amount of iodine (10 mol%) in CH2Cl2. Antibacterial and antifungal in vitro properties of the synthesized compounds were tested against some human pathogenic microorganisms by employing the disk diffusion technique. For the most active compounds, also minimum inhibitory concentrations (MICs) were determined.

  DOI：

  10.1080/10426507.2011.632387