1',2,3,3',4,4',6-hepta-O-benzyl-6'-O-hexadecylsucrose | 1261272-26-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 1',2,3,3',4,4',6-hepta-O-benzyl-6'-O-hexadecylsucrose
• CAS: 1261272-26-7
• 化学式: C₇₇H₉₆O₁₁
• 分子量: 1197.6
• InChiKey: FMYNNGMPEJHOQH-CPFFVWMNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  16.68
• 重原子数：
  88.0
• 可旋转键数：
  42.0
• 环数：
  9.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  101.53
• 氢给体数：
  0.0
• 氢受体数：
  11.0

反应信息

• 作为产物：
  描述：

  溴甲苯 、 三苯基氯甲烷 、 溴代十六烷 、 蔗糖 在 吡啶 、 sodium hydride 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 20.5h， 生成 1',2,3,3',4,4',6'-hepta-O-benzyl-6-O-hexadecylsucrose 、 1',2,3,3',4,4',6-hepta-O-benzyl-6'-O-hexadecylsucrose
  参考文献：
  名称：

  Self-assembly of 6-O- and 6′-O-hexadecylsucroses mixture under aqueous conditions

  摘要：

  In this paper we report the self-assembly of 6-O- and 6'-O-hexadecylsucroses mixture under aqueous conditions The mixture was synthesized by a five-step sequence from sucrose The SEM image of a sample prepared by drying a dispersion of the mixture in water showed nanoparticles with the diameter of similar to 50 nm and aggregates that were formed by further assembly of them The XRD measurement of the sample exhibited the diffraction pattern assignable to face-centered cubic (FCC) structure and the diameter of a sphere which took part in the FCC structure was calculated to be 5 1 nm This value was relatively close to that observed in the DLS measurement of a dispersion of the mixture in water and estimated for a spherical micelle based on the molecular sizes of the two sucrose ethers On the basis of the above findings the following self-assembly process of the mixture under aqueous conditions was proposed The mixture formed the spherical micelles with the diameter of similar to 5-7 nm in water The micelles regularly organized according to the FCC structure during the drying process from the aqueous dispersion to construct the nanoparticles with the diameter of similar to 50 nm Several numbers of the nanoparticles further assembled to form the aggregates (C) 2010 Elsevier Ltd All rights reserved

  DOI：

  10.1016/j.carres.2010.10.003