alpha-phenyl-alpha-(2-phenyl)propyl-1H-1,2,4-triazole-1-propanenitrile | 114369-46-9

• 分子结构分类: 有机化合物 - 木脂素、新木脂素和相关化合物
• 英文名称: alpha-phenyl-alpha-(2-phenyl)propyl-1H-1,2,4-triazole-1-propanenitrile
• 英文别名: 2,4-Diphenyl-2-(1,2,4-triazol-1-ylmethyl)pentanenitrile
• CAS: 114369-46-9
• 化学式: C₂₀H₂₀N₄
• 分子量: 316.406
• InChiKey: ANXWICOVGYQVRJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  24
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  54.5
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Alpha-aryl-alpha-phenylethyl-1H-1,2,4-triazole-1-propanenitriles
  申请人：ROHM AND HAAS COMPANY

  公开号：EP0251775A2

  公开（公告）日：1988-01-07

  This invention relates to certain substituted and unsubstituted alpha-aryl-alpha-phenylethyl-1-H-­1,2,4-triazole-1-propanenitriles, their enantiomorphs, acid addition salts and metal salt complexes which are active broad-spectrum systemic fungicides effective in controlling phytopathogenic fungi such as corn helminthosporium, barley helminthosporium, cucumber downy mildew, cucumber powdery mildew, cucumber anthracnose, botrytis, tomato early blight, tomato late blight, grape downy mildew, bean powdery mildew, peanut cercospora, rice blast, rice sheath blight, wheat leaf rust, wheat septoria nodorum, wheat powdery mildew and wheat stem rust. The invention also concerns a method of preparing alpha-aryl-alpha-triazolylmethyl-­acetonitrile compounds by reacting an aryl acetonitrile compound with a halomethyltriazole.

  本发明涉及某些取代和未取代的α-芳基-α-苯乙基-1-H-1,2,4-三唑-1-丙腈、其对映体、酸加成盐和金属盐复合物，它们是活性广谱系统性杀真菌剂，可有效防治植物病原真菌，如玉米螺旋孢霉、大麦螺旋孢霉、黄瓜霜霉病、黄瓜白粉病、黄瓜炭疽病、肉毒疫霉、番茄早疫病、番茄晚疫病、葡萄疫霉病、大麦螺旋孢菌、黄瓜霜霉病、黄瓜白粉病、黄瓜炭疽病、灰霉病、番茄早疫病、番茄晚疫病、葡萄霜霉病、豆类白粉病、花生孢子菌、稻瘟病、水稻鞘枯病、小麦叶锈病、小麦败酱病、小麦白粉病和小麦茎锈病。本发明还涉及一种通过芳基乙腈化合物与卤甲基三唑反应制备α-芳基-α-三唑甲基-乙腈化合物的方法。
• US5087635A
  申请人：——

  公开号：US5087635A

  公开（公告）日：1992-02-11