E-Salicylaldehyd-2-(3-methylquinolyl)hydrazon | 57876-75-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: E-Salicylaldehyd-2-(3-methylquinolyl)hydrazon
• 英文别名: 2-[(E)-[(3-methylquinolin-2-yl)hydrazinylidene]methyl]phenol
• CAS: 57876-75-2
• 化学式: C₁₇H₁₅N₃O
• 分子量: 277.326
• InChiKey: MLSPAMDZBWWARP-WOJGMQOQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• QUINOLYL HYDRAZONES FOR THE TREATMENT OF TUBERCULOSIS AND RELATED DISEASES
  申请人：TECNIMEDE-SOCIEDADE TECNICO-MEDICINAL, S.A.

  公开号：EP2934528A1

  公开（公告）日：2015-10-28
• [EN] QUINOLYL HYDRAZONES FOR THE TREATMENT OF TUBERCULOSIS AND RELATED DISEASES<br/>[FR] QUINOLYL-HYDRAZONES POUR LE TRAITEMENT DE LA TUBERCULOSE ET DE MALADIES ASSOCIÉES
  申请人：TECNIMEDE SOCIEDADE TECNICO MEDICINAL S A

  公开号：WO2014081325A1

  公开（公告）日：2014-05-30

  The invention provides quinolyl-hydrazones of Formula I, or pharmaceutically acceptable salts, esters, solvates, isomers and prodrugs thereof as well as pharmaceutical compositions containing these compounds for use in the prophylactic and/or therapeutic treatment of tuberculosis and related diseases, such as, diseases caused by nontuberculous mycobacteria and/or caused by Micobacterium leprae.