7-(1-azulenyl)-3-methyl-2,4,6-heptatrienal | 129176-31-4

• 分子结构分类: 有机化合物 - 碳氢化合物 - 不饱和烃
• 英文名称: 7-(1-azulenyl)-3-methyl-2,4,6-heptatrienal
• 英文别名: (2E,4E,6E)-7-azulen-1-yl-3-methylhepta-2,4,6-trienal
• CAS: 129176-31-4
• 化学式: C₁₈H₁₆O
• 分子量: 248.324
• InChiKey: RGXXWEXSVMMRLQ-ZOOZKBRGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  19
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  7-(1-azulenyl)-3-methyl-2,4,6-heptatrienenitrile 在 二异丁基氢化铝 作用下， 以 ether-dichloromethane 为溶剂， 生成 7-(1-azulenyl)-3-methyl-2,4,6-heptatrienal
  参考文献：
  名称：

  Azulenic retinoid compounds, compositions and methods

  摘要：

  本发明揭示了新型蓝花烯类视黄醇化合物和治疗组合物，以及它们的生产方法和作为抗癌和预防癌症剂的用途。本发明的组合物还可用于治疗皮肤疾病，如痤疮和牛皮癣，以及与皮肤相关的条件，如皱纹修复和消除。

  公开号：

  US05235076A1

文献信息

• EP0588915A4
  申请人：——

  公开号：EP0588915A4

  公开（公告）日：1995-05-31
• AZULENIC RETINOID COMPOUNDS, COMPOSITIONS AND METHODS
  申请人：UNIVERSITY OF HAWAII

  公开号：EP0588915A1

  公开（公告）日：1994-03-30
• PHOTOCHROMIC MATERIAL COMPRISING A PROTEORHODOPSIN APOPROTEIN AND RETINAL ANALOG
  申请人：GENENCOR INTERNATIONAL, INC.

  公开号：EP1753997B1

  公开（公告）日：2009-10-28
• Photochromic Material Comprising a Proteorhodopsin Apoprotein and a Retinal Analog
  申请人：Jensen Rasmus B.

  公开号：US20080290328A1

  公开（公告）日：2008-11-27

  The present invention relates to a photochromic material comprising a proteorhodopsin apoprotein and a retinal analog. In one embodiment, the retinal analog is an azulenic retinoid compound. In another embodiment, the retinal analog is a compound that is structurally similarly to all-trans-retinal. The proteorhodopsin apoprotein and the retinal analog form a photochromic material having different spectral properties from those of a corresponding photochromic material formed by the same proteorhodopsin apoprotein and all-trans-retinal. In one embodiment of the application, the retinal analog-containing proteorhodopsin has an absorbance spectrum that does not overlap significantly with that of all-trans-retinal-containing proteorhodopsin. In another embodiment of the application, the retinal analog-containing proteorhodopsin yields a red-shifted visual chromophore compared with the all-trans-retinal-containing proteorhodopsin chromophore. The photochromic material of the present invention is useful as an optical data storage carrier, a fraud-proof optical data carrier, security ink, and in other optical applications.
• Composition Comprising Various Proteorhodopsins and/or Bacteriorhodopsins and Use Thereof
  申请人：Bott Richard R.

  公开号：US20080292828A1

  公开（公告）日：2008-11-27

  The present invention provides a solid material comprising an immobilized mixture of two or more proteorhodopsins, two or more bacteriorhodopsins, or one or more bacteriorhodopsin and one or more proteorhodopsins. The proteorhodopsins are selected from the group consisting of all-trans-retinal-containing proteorhodopsins and retinal analog-containing proteorhodopsins; all of which have absorption spectra that do not overlap. The bacteriorhodopsins are selected from the group consisting of all-trans-retinal-containing bacteriorhodopsins and retinal analog-containing bacteriorhodopsins; all of which have absorption spectra that do not overlap. The present invention also provides an optical information carrier, such as an optical data storage material and a fraud-proof optical data carrier, comprising the above-described solid material and a substrate selected from the group consisting of glass, paper, metal, fabric material, and plastic material, wherein said solid material is deposited on said substrate. The present invention further provides security ink comprising one or more hydrophilic polymers and a mixture of various photochromic materials.