| 1367367-99-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 1367367-99-4
• 化学式: C₁₀H₂₃N₂O₂
• 分子量: 203.305
• InChiKey: HWGJHSABAKCDLG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.44
• 重原子数：
  14.0
• 可旋转键数：
  4.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  46.61
• 氢给体数：
  1.0
• 氢受体数：
  3.0

反应信息

• 作为产物：
  描述：

  N,N-二乙基乙酰胺 、 亚硝基叔丁烷 在 2-Ethoxy-thioxanthon 作用下， 以 乙腈 为溶剂， 生成 、
  参考文献：
  名称：

  The photoreactions of simple amides with NO. Gaining insight into radical bio-damages through an EPR case study

  摘要：

  Eight simple amides have been subjected to UV irradiation in the presence of either MNP or NO. In all cases radical species were generated: these were detected by means of EPR spectroscopy in the form of different nitroxides resulting from the trapping of the primary radicals. NO acted as a double spin trap, scavenging a radical to afford a diamagnetic nitroso derivative that in turn acted as trap towards another radical unit. As amido-groups are present in components of skin tissue and may be present in many therapeutic or cosmetic products used as skin sunscreen, and NO is a ubiquitous endogenous reactive species, the nitroxides detected in the present studies might participate in radical processes triggered by sun exposure and resulting in damages, even severe, of biological tissues. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2012.01.066