(S)-5-(3-(ethylsulfonyl)phenyl)-3,8-dimethyl-N-(piperidin-3-yl)-9H-pyrido[2,3-b]indole-7-carboxamide | 1192144-80-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: (S)-5-(3-(ethylsulfonyl)phenyl)-3,8-dimethyl-N-(piperidin-3-yl)-9H-pyrido[2,3-b]indole-7-carboxamide
• 英文别名: 5-(3-ethylsulfonylphenyl)-3,8-dimethyl-N-[(3S)-piperidin-3-yl]-9H-pyrido[2,3-b]indole-7-carboxamide
• CAS: 1192144-80-1
• 化学式: C₂₇H₃₀N₄O₃S
• 分子量: 490.626
• InChiKey: CFPNWPQVXPCHAO-IBGZPJMESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  35
• 可旋转键数：
  5
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  112
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• KINASE INHIBITORS
  申请人：Brown Jason W.

  公开号：US20090312288A1

  公开（公告）日：2009-12-17

  Compounds are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.

  提供了用于与包含从下列组中选择的化合物的激酶一起使用的化合物：其中变量如本文所定义。还提供了包含这些化合物的制药组合物、工具包和制造品；制备这些化合物的有用中间体和方法；以及使用这些化合物的方法。
• [EN] KINASE INHIBITORS<br/>[FR] INHIBITEURS DE KINASES
  申请人：TAKEDA PHARMACEUTICAL

  公开号：WO2009129401A1

  公开（公告）日：2009-10-22

  Compounds are provided for use with kinases that comprise a compound selected from the group consisting of formula (I): wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.