| 1193733-42-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 1193733-42-4
• 化学式: C₄₂H₆₅N₃O₃₁
• 分子量: 1107.98
• InChiKey: YQPHLQMAULCCCO-ILPAKNLHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -11.98
• 重原子数：
  76.0
• 可旋转键数：
  22.0
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.81
• 拓扑面积：
  544.6
• 氢给体数：
  20.0
• 氢受体数：
  31.0

反应信息

• 作为反应物：
  描述：

  、 hyaluronic acid 在 bovine testicular hyaluronidase type 1-S 作用下， 反应 1.0h， 生成 、 7,10-dibromo-1,4-diphenyl-2,3-bis(4-((3,4,5-tris(hexadecyloxy)benzyl)oxy)phenyl)triphenylene
  参考文献：
  名称：

  Novel Glycosaminoglycan Glycotechnology: Method for Hybrid Synthesis of Glycosaminoglycan Chains Utilizing Chemo-enzymatic Procedures

  摘要：

  A novel method for the synthesis of glycosaminoglycan chains is described. The 4,5-unsaturated hexuronic acid located at the nonreducing terminal, which derived from eliminase digestion of glycosaminoglycan, is chemically converted to glucuronic acid by employing the oxymercuration-demercuration reaction. Then, utilizing these oligosaccharides as acceptors for the transglycosylation reaction of bovine testicular hyaluronidase, glycosaminoglycan oligosaccharides were successfully constructed. It is thought that the present method will contribute to the development of glycosaminoglycan glycobiology and technology.

  DOI：

  10.1080/07328303.2010.514488
• 作为产物：
  描述：

  在 mercury(II) diacetate 、 sodium tetrahydroborate 作用下， 以 四氢呋喃 、 水 为溶剂， 反应 1.17h， 生成
  参考文献：
  名称：

  Novel Glycosaminoglycan Glycotechnology: Method for Hybrid Synthesis of Glycosaminoglycan Chains Utilizing Chemo-enzymatic Procedures

  摘要：

  A novel method for the synthesis of glycosaminoglycan chains is described. The 4,5-unsaturated hexuronic acid located at the nonreducing terminal, which derived from eliminase digestion of glycosaminoglycan, is chemically converted to glucuronic acid by employing the oxymercuration-demercuration reaction. Then, utilizing these oligosaccharides as acceptors for the transglycosylation reaction of bovine testicular hyaluronidase, glycosaminoglycan oligosaccharides were successfully constructed. It is thought that the present method will contribute to the development of glycosaminoglycan glycobiology and technology.

  DOI：

  10.1080/07328303.2010.514488