1-{3,5-Bis[dimethyl(1,1-dimethylethyl)silyloxy]phenoxymethyl}-4-methyl-2,5-dibromobenzene | 306272-62-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 1-{3,5-Bis[dimethyl(1,1-dimethylethyl)silyloxy]phenoxymethyl}-4-methyl-2,5-dibromobenzene
• CAS: 306272-62-8
• 化学式: C₂₆H₄₀Br₂O₃Si₂
• 分子量: 616.581
• InChiKey: QQAVAFTYAVACKO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.87
• 重原子数：
  33.0
• 可旋转键数：
  7.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  27.69
• 氢给体数：
  0.0
• 氢受体数：
  3.0

反应信息

• 作为产物：
  描述：

  1-甲基-4-(溴亚甲基)-2,5-二溴苯 在 咪唑 、 18-冠醚-6 、 potassium carbonate 作用下， 以 N,N-二甲基甲酰胺 、 丙酮 为溶剂， 反应 24.0h， 生成 1-{3,5-Bis[dimethyl(1,1-dimethylethyl)silyloxy]phenoxymethyl}-4-methyl-2,5-dibromobenzene
  参考文献：
  名称：

  Entering a New Level of Use for Suzuki Cross-Coupling: Poly(para-phenylene)s with Fourth-Generation Dendrons

  摘要：

  Three different synthetic routes to the fourth-generation (G4) macromonomers 4, 6, and 9 for Suzuki polycondensation (SPC) are described and compared in their efficiency. Monomer 9 was selected the best as judged by the number and feasibility of synthetic steps and purification behavior and could be prepared in a 15 g scare. SPC of the monomers 4, 6, and 9 gave the novel poly(para-phenylene)s 17, 18, and 19 with pendant G4 dendrons at every other repeat unit. SPC was optimized for 9 and the diboronic acid ester counterpart 16 which led to polymer 19 with a molecular weight of up to M-n=76000, M-w=639000 (GPC versus polystyrene). High molecular weight is most likely to be obtained for the attempted stoichiometry 9:16=1.000:(0.995-1.005).

  DOI：

  10.1002/1521-3765(20000901)6:17<3235::aid-chem3235>3.0.co;2-4