1,6-bis-(2,4)thiazola-cyclodecaphane | 7075-90-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 1,6-bis-(2,4)thiazola-cyclodecaphane
• 英文别名: 1,6-Bis-(2,4)thiazola-cyclodecaphan
• CAS: 7075-90-3
• 化学式: C₁₄H₁₈N₂S₂
• 分子量: 278.442
• InChiKey: KHGXIHOUEKSSCJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.04
• 重原子数：
  18.0
• 可旋转键数：
  0.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  25.78
• 氢给体数：
  0.0
• 氢受体数：
  4.0

反应信息

• 作为产物：
  描述：

  Dithioadipamid 、 1,8-dichlorooctane-2,7-dione 在 溶剂黄146 作用下， 生成 1,6-bis-(2,4)thiazola-cyclodecaphane
  参考文献：
  名称：

  据大环噻唑化合物II的知识

  摘要：

  DOI：

  10.1002/hlca.19470300223

文献信息

• Total Reconstruction of the Mitral Valve with Autopericardium: Anatomical Study
  作者：Vahe C Gasparyan、Van S Galstyan

  DOI：10.1177/021849230201000210

  日期：2002.6

  Mitral valve repair has several advantages over prosthetic valve replacement. A new technique of total reconstruction of the mitral valve with autologous pericardium is described. The native mitral valve leaflets and chordae were excised from 10 human cadaver hearts, in the same way as for prosthetic valve replacement. The dimensions of the physiologically normal mitral valve were used to calculate the parameters for tailoring a corresponding new valve. Autologous pericardium was fixed in 0.625% glutaraldehyde solution for 10 minutes. The calculated parameters of the mitral valve were marked on the pericardium. The new valve was fashioned and inserted in the native valve position. Hydraulic probes showed good competence in all 10 reconstructed mitral valves. This method might be a good alternative to prosthetic valve replacement.

  二尖瓣修复比假体瓣膜置换有几个优点。本文描述了一种新的使用自体心包完全重建二尖瓣的技术。与假体瓣膜置换相同，从10个人类尸体心脏中切除了本身的二尖瓣叶片和腱索。使用生理正常二尖瓣的尺寸计算了裁剪相应新瓣膜所需的参数。自体心包在0.625％戊二醛溶液中固定10分钟。二尖瓣的计算参数标记在心包上。新的瓣膜被制作并插入本身的瓣膜位置。水力探针显示所有10个重建的二尖瓣都具有良好的功能。这种方法可能是假体瓣膜置换的良好替代品。
• Erlenmeyer; Degen, Helvetica Chimica Acta, 1946, vol. 29, p. 1081
  作者：Erlenmeyer、Degen

  DOI：——

  日期：——
• Erlenmeyer; Buechler, Helvetica Chimica Acta, 1944, vol. 29, p. 1927
  作者：Erlenmeyer、Buechler

  DOI：——

  日期：——