2-ethyldodecanal | 33861-29-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-ethyldodecanal
• CAS: 33861-29-9
• 化学式: C₁₄H₂₈O
• 分子量: 212.376
• InChiKey: ONDFOFWKYWTFMV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.8
• 重原子数：
  15
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  2-乙基-1-十二醇 在 重铬酸吡啶 作用下， 以 二氯甲烷 为溶剂， 以55%的产率得到2-ethyldodecanal
  参考文献：
  名称：

  Ethyl-Branched Aldehydes, Ketones, and Diketones from Caimans (Caiman and Paleosuchus; Crocodylia, Reptilia)

  摘要：

  Secretions from the paracloacal glands of alligators (Alligator spp.) and caimans (Caiman spp., Melanosuchus niger, and Paleosuchus spp.) were examined by GC-MS. The secretions of the common caiman (C. crocodilus), the broadsnouted caiman (C. latirostris), the yacare caiman (C. yacare), the dwarf caiman (P. palpebrosus), and the smooth-fronted caiman (P. trigonatus) yielded a new family of 43 aliphatic carbonyl compounds that includes aldehydes, ketones, and beta-diketones with an ethyl branch adjacent to the carbonyl group. The identification of these glandular components and the syntheses and stereochemical investigations of selected compounds are described.

  DOI：

  10.1021/np0600797

文献信息

• Method for Producing Aldehyde and Ketone
  申请人：Yamashita Miyoshi

  公开号：US20110282102A1

  公开（公告）日：2011-11-17

  Provided is a highly efficient method for the production of aldehydes and ketones, which is inexpensive, exhibits high reactivity, and is capable of easy separation of byproduct after the reaction. More particularly, there is provided a method for producing an aldehyde or a ketone, comprising at least an oxidation step of oxidizing a primary alcohol or a secondary alcohol in the presence of a polymeric carbodiimide represented by the following formula (1) and having a weight-average molecular weight of 300 to 5000, and a sulfoxide compound, together with an acid and a base, or together with a salt of the acid and the base.

  提供了一种高效的生产醛和酮的方法，该方法廉价、具有高反应性，并能够在反应后轻松分离副产物。更具体地，提供了一种生产醛或酮的方法，包括至少一个氧化步骤，即在聚合物碳二亚胺（表示为以下式（1）且具有分子量为300至5000的重均分子量）和亚砜化合物的存在下氧化一级醇或二级醇，以及酸和碱，或者酸和碱的盐。
• Tandem Carbocupration/Oxygenation of Terminal Alkynes
  作者：Donghui Zhang、Joseph M. Ready

  DOI：10.1021/ol052413g

  日期：2005.12.1

  their enol derivatives is described. Carbocupration of terminal alkynes and subsequent oxygenation with lithium tert-butyl peroxide generates a metallo-enolate. Trapping with various electrophiles provides alpha-branched aldehydes or stereo-defined trisubstituted enol esters or silyl ethers. The tandem carbocupration/oxygenation tolerates alkyl and silyl ethers, esters, and tertiary amines. The reaction

  [化学反应：见正文]。描述了α-支化醛及其烯醇衍生物的直接和一般合成。末端炔烃的碳化和随后用叔丁基过氧化锂的氧合生成金属烯醇盐。与各种亲电试剂的陷阱提供了α-支链的醛或立体定义的三取代的烯醇酯或甲硅烷基醚。串联碳cup合/加氧可耐受烷基和甲硅烷基醚，酯和叔胺。该反应对衍生自伯，仲和叔格氏试剂和正丁基锂的有机铜配合物有效。
• Process for catalyst-aldehyde product separation
  申请人：UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (a New York corporation)

  公开号：EP0350922A2

  公开（公告）日：1990-01-17

  Process for the separation and recovery of aldehyde product from a non-aqueous hydroformylation reaction product composition comprising the aldehyde product, a rhodium-ionically charged phosphorus ligand complex, a free ionically charged phosphorus ligand and an organic solubilizing agent for said complex and said free ligand via phase separation using added water or both added water and an added non-polar hydrocarbon compound.

  从非水加氢甲酰化反应产物组合物中分离和回收醛产物的工艺，该组合物包括醛产物、铑-带离子电荷的磷配位体络合物、游离的带离子电荷的磷配位体以及用于所述络合物和游离配位体的有机增溶剂，通过使用添加的水或添加的水和添加的非极性烃化合物进行相分离。
• Reactivation of hydroformylation catalysts
  申请人：UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION

  公开号：EP0552797A1

  公开（公告）日：1993-07-28

  A process for improving the catalytic activity of a partially deactivated solubilized rhodium - tertiary organophosphine complex hydroformylation catalyst by treating it with propargyl alcohol and a carboxylic acid.

  一种用丙炔醇和羧酸处理部分失活的溶解铑-叔有机膦络合物加氢甲酰化催化剂以提高其催化活性的工艺。
• Method for producing aldehyde and ketone
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：EP2386535A1

  公开（公告）日：2011-11-16

  Provided is a highly efficient method for the production of aldehydes and ketones, which is inexpensive, exhibits high reactivity, and is capable of easy separation of byproduct after the reaction. More particularly, there is provided a method for producing an aldehyde or a ketone, comprising at least an oxidation step of oxidizing a primary alcohol or a secondary alcohol in the presence of a polymeric carbodiimide represented by the following formula (1) and having a weight-average molecular weight of 300 to 5000, and a sulfoxide compound, together with an acid and a base, or together with a salt of the acid and the base.          R1―N=C=N―(R3―N=C=N)―nR2     (1)

  本发明提供了一种生产醛和酮的高效方法，该方法成本低廉，反应活性高，且反应后的副产物易于分离。更具体地说，本发明提供了一种生产醛或酮的方法，该方法至少包括一个氧化步骤，即在由下式（1）表示的、重量平均分子量为 300 至 5000 的聚合物碳二亚胺和亚砜化合物以及酸和碱或酸和碱的盐的存在下，氧化伯醇或仲醇。 R1-N=C=N-(R3-N=C=N)-nR2 (1)